Results 101 to 110 of about 34,807 (305)

An Efficient Series Solution for Nonlinear Multiterm Fractional Differential Equations

Discrete Dynamics in Nature and Society, 2017
In this paper, we introduce an efficient series solution for a class of nonlinear multiterm fractional differential equations of Caputo type. The approach is a generalization to our recent work for single fractional differential equations.
Moh’d Khier Al-Srihin, Mohammed Al-Refai   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Dispersive wave solutions of the nonlinear fractional Zakhorov-Kuznetsov-Benjamin-Bona-Mahony equation and fractional symmetric regularized long wave equation

Results in Physics, 2019
In this paper, we obtain several novelty solutions by applying the improved F-expansion method to solve the space–time fractional Zakhorov Kuznetsov Benjamin Bona Mahony (ZKBBM) equation and the space–time fractional symmetric regularized long wave (SRLW)
David Yaro, Aly R. Seadawy, Dianchen Lu, Wilson Osafo Apeanti, Saviour Worlanyo Akuamoah   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Schrödinger Potentials with Polynomial Solutions of Heun-Type Equations

Mathematics
The present review discusses the solution of the Heun, confluent, biconfluent, double confluent, and triconfluent equations in terms of polynomial expansions, and applies the results to generate exactly solvable Schrödinger potentials. Although there are
Géza Lévai, Tibor Soltész
doaj   +1 more source

The new approach of the generalized (G′/G)-expansion method for nonlinear evolution equations

Ain Shams Engineering Journal, 2014
In this article, we apply the new generalized (G′/G)-expansion method to solve two nonlinear partial differential equations and construct traveling wave solutions in terms of hyperbolic functions, trigonometric functions, and rational functions with ...
Md. Nur Alam, M. Ali Akbar
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Uniform cohomological expansion of uniformly quasiregular mappings [PDF]

, 2019
Let f:M -> M be a uniformly quasiregular self-map of a compact, connected, and oriented Riemannian n-manifold M without boundary, n > 2. We show that, for k is an element of{0, horizontal ellipsis ,n}, the induced homomorphism f*:Hk(M;R)-> Hk(M;R), where
Kangasniemi, Ilmari, Pankka, Pekka
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

A Shifted Jacobi-Gauss Collocation Scheme for Solving Fractional Neutral Functional-Differential Equations

Advances in Mathematical Physics, 2014
The shifted Jacobi-Gauss collocation (SJGC) scheme is proposed and implemented to solve the fractional neutral functional-differential equations with proportional delays.
A. H. Bhrawy, M. A. Alghamdi
doaj   +1 more source