Results 91 to 100 of about 720,223 (381)

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

Student difficulties with determining expectation values in quantum mechanics [PDF]

open access: yes, 2017
The expectation value of an observable is an important concept in quantum mechanics. However, upper-level undergraduate and graduate students in physics have both conceptual and procedural difficulties when determining the expectation value of physical observables, especially when using Dirac notation. To investigate these difficulties, we administered
arxiv   +1 more source

Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?

open access: yesOxidative Medicine and Cellular Longevity, 2016
The recognition that food-derived nonnutrient molecules can modulate gene expression to influence intracellular molecular mechanisms has seen the emergence of the fields of nutrigenomics and nutrigenetics.
C. Houghton, R. Fassett, J. Coombes
semanticscholar   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Lay understanding of probability distributions

open access: yesJudgment and Decision Making, 2014
How accurate are laypeople’s intuitions about probability distributions of events? The economic and psychological literatures provide opposing answers.
Daniel G. Goldstein, David Rothschild
doaj   +1 more source

The role of beliefs, expectations and values in decision-making favoring climate change adaptation—implications for communications with European forest professionals

open access: yesEnvironmental Research Letters, 2020
Beliefs, expectations and values are often assumed to drive decisions about climate change adaptation. We tested hypotheses based on this assumption using survey responses from 508 European forest professionals in ten countries.
K Blennow   +14 more
doaj   +1 more source

Tightness, weak compactness of nonlinear expectations and application to CLT [PDF]

open access: yesarXiv, 2010
In this paper we introduce a notion of tightness for a family of nonlinear expectations and show that the tightness can be applied to obtain weak compactness in a framework of nonlinear expectation space. This criterion is very useful for obtaining the weak convergence for a sequence of nonlinear expectations, which is a equivalent to the so-called ...
arxiv  

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Does unfairness sound wrong? A cross-domain investigation of expectations in music and social decision-making

open access: yesRoyal Society Open Science, 2020
This study was interested in investigating the existence of a shared psychological mechanism for the processing of expectations across domains. The literature on music and language shows that violations of expectations produce similar neural responses ...
Claudia Civai   +2 more
doaj   +1 more source

Expected Information as Expected Utility

open access: yesThe Annals of Statistics, 1979
The normative procedure for the design of an experiment is to select a utility function, assess the probabilities, and to choose that design of maximum expected utility. One difficulty with this view is that a scientist typically does not have, nor can be normally expected to have, a clear idea of the utility of his results. An alternative is to design
openaire   +3 more sources

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