Results 91 to 100 of about 2,520,095 (363)

Rapid learning of pursuit target motion trajectories revealed by responses to randomized transient sinusoids

open access: yesJournal of Eye Movement Research, 2012
When humans pursue sinusoidal target motion they rapidly learn to track with minimal phase error despite inherent visuo-motor processing delays; prior evidence suggests that prediction might even occur within the first cycle. Here, this has been examined
Graham R. Barnes
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Fermionic current densities induced by magnetic flux in a conical space with a circular boundary

open access: yes, 2010
We investigate the vacuum expectation value of the fermionic current induced by a magnetic flux in a (2+1)-dimensional conical spacetime in the presence of a circular boundary. On the boundary the fermionic field obeys MIT bag boundary condition.
A. A. Saharian   +15 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Growth Expectation [PDF]

open access: yes
For a long time, changes in expectations about the future have been thought to be significant sources of economic fluctuations, as argued by Pigou (1926).
Ippei Fujiwara
core  

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Great expectations [PDF]

open access: yesAmerican Journal of Transplantation, 2022
Kenneth A. Newell, Christian P. Larsen
openaire   +4 more sources

Breathlessness and the brain: the role of expectation

open access: yesCurrent Opinion in Supportive and Palliative Care, 2019
Purpose of review Breathlessness debilitates countless people with a wide range of common diseases. For some people, the experience of breathlessness is poorly explained by the findings of medical tests.
Lucy Marlow   +3 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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