Results 111 to 120 of about 620,577 (299)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Expectation-maximization approaches to independent component analysis
, 2004 Expectation-Maximization (EM) algorithms for independent component analysis are presented in this paper. For super-Gaussian sources, a variational method is employed to develop an EM algorithm in closed form for learning the mixing matrix and inferring ...
Zhong, MJ, Tang, HW, Tang, YY
core +1 more source
International Journal of Qualitative Studies on Health & Well-BeingParticipation in a paediatric, complex randomized controlled trial (RCT) might add to the family burden when a child is diagnosed with a severe disease. Although important, there are only a limited number of papers describing this aspect of research from
Peter Sand +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Switching Between Expectation Processes in the Foreign Exchange Market: A Probabilistic Approach Using Survey Data [PDF]
This paper relaxes a fundamental hypothesis commonly accepted in the expectation formation literature: expectations are, unchangingly, either rational or generated by one of the three simple extrapolative, regressive or adaptive processes.
Georges Prat, Remzi Uctum
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
BİYOÇEŞİTLİLİK VE TÜRKİYE BİYOÇEŞİTLİLİĞİNE GENEL BİR BAKIŞ
Sakarya Üniversitesi Eğitim Fakültesi Dergisi, 2013 BİYOÇEŞİTLİLİK VE TÜRKİYE BİYOÇEŞİTLİLİĞİNE GENEL BİR ...
Ali Uzun
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source