Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Contextual effects in musculoskeletal pain: are we overlooking essential factors?
David Poulter +11 more
doaj +1 more source
Dynamic positron emission tomography image reconstruction using spatiotemporal kernel method with deep image prior. [PDF]
Zhao Z +5 more
europepmc +1 more source
Expectation-driven cycles in the housing market: Evidence from survey data
Luisa Lambertini +2 more
openalex +2 more sources
Initial study of neutral post-instruction responses on the Maryland Physics Expectation Survey [PDF]
Jennifer Saltzman +2 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Affective observation guides expectations about others' emotional reactions to unfamiliar action outcomes. [PDF]
Ganzetti T +3 more
europepmc +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Variational quantum generative modeling by sampling expectation values of tunable observables. [PDF]
Shen K +5 more
europepmc +1 more source

