MIF as an oncogenic driver of low‐heterogeneity melanomas
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran+4 more
wiley +1 more source
Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling+5 more
wiley +1 more source
Discrete Repetition Effects for Visual Words Compared to Faces and Animals, but No Modulation by Expectation: An Event-Related Potential Study. [PDF]
Song B, Sommer W, Maurer U.
europepmc +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Statistical process control to monitor use of a web‐based autoplanning tool
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens+5 more
wiley +1 more source
Determination of probability density, position and momentum uncertainties, and information theoretic measures using a class of inversely quadratic Yukawa potential. [PDF]
Inyang EP+5 more
europepmc +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Impact of flexible noise control (FNC) image processing parameters on portable chest radiography
Abstract There is a lack of understanding in the performance of flexible noise control (FNC) processing, which is used in digital radiography on a scanner vendor and has four parameters each involving multiple options. The aim of this study was to investigate the impact of FNC on portable chest imaging. An anthropomorphic chest phantom was imaged using
Krystal M. Kirby+6 more
wiley +1 more source
Eyes on the past: Gaze stability differs between temporal expectation and temporal attention. [PDF]
Duyar A, Carrasco M.
europepmc +1 more source