Results 41 to 50 of about 5,523,047 (289)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Reweighting Augmented Samples by Minimizing the Maximal Expected Loss [PDF]

open access: green, 2021
Mingyang Yi   +5 more
openalex   +3 more sources

Job loss and depression: The role of subjective expectations [PDF]

open access: yesSocial Science & Medicine, 2011
Although the importance of expectations is well documented in the decision-making literature, a key shortcoming of the empirical research into effects of involuntary job loss on depression is perhaps its neglect of the subjective expectations of job loss.
Mandal, Bidisha   +2 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Measuring Risk When Expected Losses Are Unbounded [PDF]

open access: yesRisks, 2014
This paper proposes a new method to introduce coherent risk measures for risks with infinite expectation, such as those characterized by some Pareto distributions. Extensions of the conditional value at risk, the weighted conditional value at risk and other examples are given.
Alejandro Balbás   +2 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Expected loss analysis of thresholded authentication protocols in noisy conditions [PDF]

open access: yes, 2010
A number of authentication protocols have been proposed recently, where at least some part of the authentication is performed during a phase, lasting $n$ rounds, with no error correction.
Dimitrakakis, Christos   +2 more
core   +2 more sources

Magnetic Field Dependent Microwave Losses in Superconducting Niobium Microstrip Resonators

open access: yes, 2018
We describe an experimental protocol to characterize magnetic field dependent microwave losses in superconducting niobium microstrip resonators. Our approach provides a unified view that covers two well-known magnetic field dependent loss mechanisms ...
Benningshof, Olaf W. B.   +10 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Expected job loss in East Germany shortly before German unification [PDF]

open access: yes
We investigate expectations concerning future job loss in the former German Democratic Republic shortly before the economic, monetary and social union in July 1990.
Giesecke O'Shea, Linda   +2 more
core  

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