Results 51 to 60 of about 6,405,842 (302)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Economic Value of Forecasts in Reducing Extreme Total Losses
Meteorological ApplicationsA major aim of weather and other types of environmental forecasting is to provide early warning of extreme hazards that can then be used to take preventative actions to reduce loss.
David B. Stephenson
doaj +1 more source
Use of Bayesian Analysis in Medical Domain [PDF]
The Egyptian Statistical Journal, 1996 This paper is concerned with the use of Bayesian analysis in women health diagnosis. Illustration example is given on real data collected from women at high risk pregnancy. A suggested coding for the classification in a multidimensional symptom space for
Aida A. El.Batran, El Houssainy A. Rady
doaj +1 more source
Mapping Life Expectancy Loss in Barcelona in 2020
The American Statistician, 2023 We use a Bayesian spatio-temporal model, first to smooth small-area initial life expectancy estimates inBarcelona for 2020, and second to predict what small-area life expectancy would have been in 2020 inabsence of covid-19 using mortality data from 2007 to 2019.
Puig Oriol, Xavier +1 more
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Blind Image Deblurring via Bayesian Estimation Using Expected Loss
IEEE AccessThis paper introduces a new approach to single image blind deblurring via Bayesian estimation using expected loss, diverging from traditional maximum a posteriori (MAP) estimation methods that are limited by the delta kernel problem-a phenomenon where ...
Jinook Lee, Moon Gi Kang
doaj +1 more source
Limitations of Implementing an Expected Credit Loss Model
SSRN Electronic Journal, 2023 The loan impairment rules recently introduced by IFRS 9 require banks to estimate their future credit losses by using forward-looking information. We use supervisory loan-level data from Germany to investigate how banks apply their reporting discretion and adjust their lending upon the announcement of the new rules. Our identification strategy exploits
Bischof, Jannis +3 more
openaire +4 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Loss Modification Incentives for Insurers under Expected Utility and Loss Aversion [PDF]
SSRN Electronic Journal, 2014 We investigate whether a profit-maximizing insurer with the opportunity to modify the loss probability will engage in loss prevention or instead spend effort to increase the loss probability. First we study this question within a traditional expected utility framework; then we apply Koszegi and Rabin's (2006, 2007) loss aversion model to account for ...
Adriaan R. Soetevent, Liting Zhou
openaire +8 more sources