Results 101 to 110 of about 2,833,553 (287)
The Mixed Reality Toolkit as the Next Step in the Mass Customization Co-Design Experience
International Journal of Industrial Engineering and Management, 2019 The mass customization (MC) toolkit is the major enabler of relational value for consumers. Not a new concept, but nascent in the context of the MC co-design experience, mixed reality (MR) merges the real and virtual world.
Frances Turner, Ian Welch
doaj +1 more source
An ontology co-design method for the co-creation of a continuous care ontology [PDF]
, 2014 Ontology engineering methodologies tend to emphasize the role of the knowledge engineer or require a very active role of domain experts. In this paper, a participatory ontology engineering method is described that holds the middle ground between these ...
Ackaert, Ann +9 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Improving the Aerospace Capstone Design Experience Through Simulation Based Learning [PDF]
, 2012 A key role of universities is to prepare students to work in their chosen profession upon completion of their degree program. Engineering capstone design courses are often the only required courses that challenge students to draw on nearly all of the ...
Butler, Wm. Michael +5 more
core +3 more sources
Student staff partnership to create an interdisciplinary science skills course in a research intensive university [PDF]
, 2015 This paper reflects upon the development of a multidisciplinary lesson plan aimed at developing science skills for Physics and Astronomy, Geographical and Earth Sciences, and Chemistry students at a research intensive Scottish university. The lesson plan
Curry, Gordon +6 more
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Experience-Based Co-Design to Develop an Injury Prevention Intervention in Skilled Nursing Facilities [PDF]
Innov Aging, 2020 Abstract Experience-based co-design (EBCD) improves clinical effectiveness and safety by incorporating end-user perspectives in the design of clinical interventions. To refine a centralized, multi-component fall-related injury prevention service (IPS) to be tested in skilled nursing facilities (SNFs) in a pragmatic trial, we employed a ...
McConnell E +4 more
europepmc +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Pervasive healthcare in lived experience : thinking beyond the home : position paper for workshop on pervasive healthcare in the home. [PDF]
The National Health Service (NHS) in the UK, like many other public heath services worldwide, is facing a number of key challenges. Among them are an ageing population and a rising incidence of chronic health conditions.
Bowen, Simon +5 more
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source