Results 41 to 50 of about 3,767,102 (309)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Alter users’ experience through service design : enabling self-awareness and responsibilities [PDF]

open access: yes, 2019
User experience is widely used in the field of service design. The definition of ‘user’ and the scope of experience varies from person to person depending on the context in which the word is used.
Shi, Mengchi
core  

Design perception and consumer-brand relationshipin textile apparel: Mediating role of experiential value and moderating role of openness to experience

open access: yesBusiness Review, 2021
Pakistan's fashion and apparel market has shown comprehensive growth during the last decade. This paper aims to investigate the impact of design perception on consumer based brand equity and examines the mediating role of experiential value and ...
Rohail Jibran   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Nature and role of intermediate representation (IR) in the design process [PDF]

open access: yes, 2005
This paper aims to show the key role of the intermediate representations (IR) in the design process and especially in the car design process. For a better understanding of the concept of design, which is by nature conceptual, we propose to study the ...
AOUSSAT, Améziane   +2 more
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Design of virtual circuit experiment based on the LabVIEW [PDF]

open access: yesAdvances in Engineering Research, 2015
Abstract: This article is designed by the LabVIEW circuit experiment module, common in the course each module specific program design scheme is given, and ultimately successful debugging operation. Based on the introduction of virtual instrument, can not only save costs, and to update and adjust teaching methods and means to make laboratory equipment ...
openaire   +1 more source

Qbro: A holistic approach to sustainable medical textiles focused on circular design and user experience

open access: yes, 2021
Disposable medical textiles, essential for health work, have assumed particular relevance in recent months because of the COVID-19 crisis. In Chile, their consumption exceeds hundreds of millions of units per year.
Gonzalez Ramos, Alberto, De lara, Ana
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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