Results 141 to 150 of about 5,358,410 (308)

Transforming Community‐Based Rehabilitation Services: A National Redesign Using Experience‐Based Co‐Design

Health Expectations
Background To understand the experiences of clients, caregivers and staff in community day rehabilitation centres (DRCs) and identify areas for improvement in service processes and the clinical care of stroke, frailty and hip fracture, a national quality
Shamala Thilarajah, Karina Dancza, Zhen Zhen Chen, Clara X. Q. Wong, Clement C. Yan, Susan Niam, Yee Sien Ng, Elizabeth Lynch, Leonid Churilov, Wei Kang Tan, Emelin Tan, Li Khim Kwah   +11 more
doaj   +1 more source

Developing an IS-impact decision tool: A literature based design science roadmap [PDF]

, 2011
This paper derives from research-in-progress intending both Design Research (DR) and Design Science (DS) outputs; the former a management decision tool based in IS-Impact (Gable et al.
Al Turki, Ahmad, Bandara, Wasana, Gable, Guy   +2 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Child–Nature-Based Experiences in Urban Preschools: A Comparative Analysis of Intervention Using User Participation Design

Proceedings
Regular exposure to natural environments significantly supports children’s holistic learning and overall health and well-being [...]
Farhana Mohammed Isa, David Grierson, Ombretta Romice   +2 more
doaj   +1 more source

Using grounded theory approach: theoretical and practical issues in modelling heritage visitor experience [PDF]

, 2004
Purpose ? The purpose of this paper is to present grounded theory as an alternative approach for conceptualizing and modelling the consumer experience.
Daengbuppha, Jaruwan, Hemmington, Nigel, Wilkes, Keith   +2 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Adapting Experience‐Based Co‐Design to Disability Research: Co‐Producing the CycLink Co‐Design Study

Health Expectations
Introduction Participatory methods like experience‐based co‐design (EBCD) can be used to develop complex interventions, but may need adaptations when co‐designers include young people with disability, parents and community partners.
John Joseph Carey, Alicia Spittle, Christine Imms, Nora Shields, Margaret Wallen, Finn O'Keefe, Miriam Joy Yates, Holly Skilbeck, Rachel Toovey   +8 more
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Lessons learned spanning 17 years of experience with three consecutive nationwide competency based medical education training plans

Frontiers in Medicine
IntroductionCurricula for postgraduate medical education have transformed since the introduction of competency based medical education (CBME). Postgraduate training plans offer broader training with different competencies and an outcome-based approach ...
Merel H. de Heer, Erik W. Driessen, Pim W. Teunissen, Pim W. Teunissen, Fedde Scheele, Fedde Scheele   +5 more
doaj   +1 more source