Results 51 to 60 of about 143,746 (258)

Planning for science: China’s “grand experiment” and global implications

open access: yesHumanities & Social Sciences Communications, 2021
China’s rising capability in science, technology and innovation to a certain extent has to do with “a grand experiment” that started 15 years ago when the Chinese government released the National Medium and Long-Term Plan for the Development of Science ...
Yutao Sun, Cong Cao
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

THE IVESTIGATION OF LIQUID-MOVING SELF-FIRMING MIXTURE FOR STEEL CASTING FORMS IN ORDER TO OPTIMIZE ITS CONTENT

open access: yesAdvanced Engineering Research, 2010
The aim of the optimization of the liquid-moving self-firming mixture (LSM) content together with the regenerated sand for making steel shaped casting forms is discussed.
Y.A. ZINCHENKO
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Empirical Information Metrics for Prediction Power and Experiment Planning

open access: yesInformation, 2011
In principle, information theory could provide useful metrics for statistical inference. In practice this is impeded by divergent assumptions: Information theory assumes the joint distribution of variables of interest is known, whereas in statistical ...
Christopher Lee
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Search for optimal parameters of wire electrical discharge machining of parts made from E110 zirconium alloy

open access: yesОмский научный вестник
The article proposes a method for calculating rational parameters of wire electrical discharge machining of zirconium alloy E110 using a rotatable central composite design of the second order.
N. V. Bobkov   +4 more
doaj   +1 more source

Differences and commonalities impregnation of dry and wet sand [PDF]

open access: yesTransport Problems, 2014
The article is devoted to research new methods of physic-chemical methods of preventing deflation to protect railways and highways from such phenomena as exogenous sand drifts.
Maujuda МUZAFFAROVA   +1 more
doaj  

Experiment Planning for Software Development: Redevelopment Experiment. [PDF]

open access: yes, 1988
The Application of Reusable Software Components Project (ARSC) formulated an experiment design, data collection plan, and procedures in preparation for a reuse experiment. The reuse experiment is currently in progress and the experiment planning and the results to date are presented.
Perry, James M.   +4 more
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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