Results 131 to 140 of about 3,019,422 (250)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Uncovering the Mechanism of Curcuma in the Treatment of Ulcerative Colitis Based on Network Pharmacology, Molecular Docking Technology, and Experiment Verification. [PDF]
Evid Based Complement Alternat Med, 2021 Liu S +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Development and Performance Validation of an Indirect Continuously Variable Transmission
Jixie chuandong, 2018 Comparing with traditional pulley transmissions,a new configuration of indirect Continuously Variable Transmissions（CVT） is proposed to enhance the driving torque and reduce the complexity of control logic.
Tang Zhirong, Ji Jie, Chen Peng, Shu Xin
doaj
Chicago Summer Institute 2012 - Truth, and Verification
, 2010 A PowerPoint presentation on the lesson on "Truth and Verification." Topics include: how journalist's pursue truth, what is truth, the verification process and how it works, kinds evidence consumers should look for, lessons for the news consumer, truth ...
Stony Brook University. School of Journalism. Center for News Literacy.
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Report of the Guam Agricultural Experiment Station.
, 1915 Mode of access: Internet.Continued by: Annual report (Guam Agricultural Experiment Station)Continues: Guam Agricultural Experiment Station. Annual report of the Guam Agricultural Experiment Station for .
Guam Agricultural Experiment Station.
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Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source