Results 101 to 110 of about 8,671,015 (345)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Experimental Hypersonic Aerodynamics and Advances in Aerospace Engineering [PDF]
فناوری در مهندسی هوافضا, 2017 Most space missions fall in the hypersonic reentry regime. There are several open questions and unknown phenomena in aerothermodynamics around vehicles at flow regimes exceeding Mach 4 due to its inherent complexities.
Shahed Malekipour, Mohammad Ebrahimi
doaj
An experimental study of airfoil-spoiler aerodynamics [PDF]
The steady/unsteady flow field generated by a typical two dimensional airfoil with a statically deflected flap type spoiler was investigated. Subsonic wind tunnel tests were made over a range of parameters: spoiler deflection, angle of attack, and two ...
Karamcheti, K., Mclachlan, B. G.
core +1 more source
A New Actuator Surface Model with Improved Wake Model for CFD Simulations of Rotorcraft [PDF]
, 2017 Simulations of rotorcraft operating in unsteady flow-fields, manoeuvring flight, or with complex rotor configurations pose a significant challenge to current simulation methods.
Barakos, Geogre +3 more
core
The Collaborative Development of New CFD Methods Adapted for Tilt Rotor Aircraft in the HiPerTilt Project [PDF]
, 2017 No abstract ...
Bevan R. V. +8 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Simulation of wind turbine wake interaction using the vorticity transport model [PDF]
, 2010 The aerodynamic interactions that can occur within a wind farm can result in the constituent turbines generating a lower power output than would be possible if each of the turbines were operated in isolation.
Ahlin +15 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ground Effect Influence on UAV Propeller Thrust: Experimental and CFD Validation
TechnologiesThis work investigates the influence of ground effect on the performance of a UAV propeller through a combined experimental, analytical, and numerical approach.
Mădălin Dombrovschi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source