Results 121 to 130 of about 9,547 (313)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Experimental Determination of Pitch Damping Coefficient Using Free Oscillation Method

open access: yesAerospace
This paper outlines an experimental investigation conducted at the INCAS trisonic wind tunnel, focusing on the determination of pitch damping coefficient. The model used for this investigation is the Basic Finner Model, a standard model for dynamic tests
Ionuț Bunescu   +2 more
doaj   +1 more source

Experimental Study of the Aerodynamics of Sail in Natural Wind

open access: yesPolish Maritime Research, 2018
In order to evaluate the impacts of a motor vessel after installing wind sails, the aerodynamics of the sail should be accurately calculated. However most of the research on sails are based on stable wind instead of natural wind which is changing ...
Xiangming Zeng, Huawu Zhang
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

High resolution schemes for bluff-body aerodynamics [PDF]

open access: yes, 2013
This MSc by Research study has been conducted with the application of a variety of grid configurations for extensive grid analysis along with various numerical schemes on the Ahmed body benchmark test case, in both 2D and 3D analysis.
Nakos, Dimitrios
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Current Status and Prospects for Experimental Aerodynamics [PDF]

open access: yes, 2002
The current status of experimental aerodynamics is characterised by highly advanced wind tunnel techniques with complex models and measuring techniques on a sophisticated level.
Kompenhans, J., Bütefisch, K.-A.
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Aerodynamics simulations of ground vehicles in unsteady crosswind [Elektronisk resurs] [PDF]

open access: yes, 2011
Ground vehicles, both on roads or on rail, are sensitive to crosswinds and the handling, travelling speeds or in some cases, safety can be affected.
Efraimsson, Gunilla,   +2 more
core  

Unsteady three-dimensional interaction between propeller tip vortices and a downstream turbulent boundary layer

open access: yesFlow
This study quantifies the viscous interaction between propeller tip vortices and a turbulent boundary layer developing over a semi-elliptic leading-edge plate, located downstream.
Aaron Duane Sequeira   +3 more
doaj   +1 more source

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