Results 61 to 70 of about 8,671,015 (345)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Wind Tunnel Investigation of Transient Propeller Loads for Non-Axial Inflow Conditions
AerospaceRecent developments in electrical Vertical Take-off and Landing (eVTOL) vehicles show the need for a better understanding of transient aero-mechanical propeller loads for non-axial inflow conditions.
Catharina Moreira +2 more
doaj +1 more source
Influence of Embankments with Parapets on the Cross-Wind Turbulence Intensity at the Contact Wire of Railway Overheads [PDF]
, 2010 Winds as an environmental factor can cause significant difficulties for the railway system operation. The railway overhead has been particularly vulnerable to cross-winds related problems, such as development of undamped oscillations due to galloping ...
Avila Sanchez, Sergio +2 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Mechanical Engineering and Sciences, 2022 The aeronautics studies and particularly the development of drones represent an important field, in which there is a very large number of research and studies.This article aims to present an experimental aerodynamic study of an autonomous surveillance ...
Djamel Kaddouri +3 more
doaj +1 more source
Helicopter Fuselage Drag ─ Combined Computational Fluid Dynamics and Experimental Studies [PDF]
, 2015 In this paper, wind tunnel experiments are combined with Computational Fluid Dynamics (CFD) aiming to analyze the aerodynamics of realistic fuselage con¦gurations.
Barakos, G. +7 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Influence of blade aerodynamic model on prediction of helicopter rotor aeroacoustic signatures [PDF]
, 2011 Brown’s vorticity transport model has been used to investigate how the local blade aerodynamic model influences the quality of the prediction of the high-frequency airloads associated with blade–vortex interactions, and thus the accuracy with which the ...
Boyd D. D. +14 more
core +1 more source
Experimental Study of Owl-Like Airfoil Aerodynamics at Low Reynolds Numbers
, 2018 This study experimentally investigates aerodynamic characteristics and flow fields of a smooth owl-like airfoil without serrations and velvet structures.
M. Anyoji +3 more
semanticscholar +1 more source