Results 71 to 80 of about 8,671,015 (345)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Experimental investigation of transonic oscillating cascade aerodynamics [PDF]
27th Aerospace Sciences Meeting, 1989 Fundamental experiments are performed in the NASA Lewis Transonic Oscillating Cascade Facility to investigate the subsonic and transonic aerodynamics of cascaded airfoils executing torsion mode oscillations at realistic values of reduced frequency. In particular, an unsteady aerodynamic influence coefficient technique is developed and utilized. In this
DANIEL BUFFUM, SANFORD FLEETER
openaire +1 more source
Etude numérique et expérimentale de l'écoulement autour d'un rotor éolien [PDF]
, 2013 An improved model of an actuator surface is proposed, representing the flow around a wind turbine. This model was developed in conjunction with a Navier-Stokes solver using a blade element method for the calculation of power and wake development.
DOBREV, Ivan +2 more
core +4 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Design, Development and Testing of Shape Shifting Wing Model
Aerospace, 2017 The design and development of morphing (shape shifting) aircraft wings—an innovative technology that has the potential to increase the aerodynamic efficiency and reduce noise signatures of aircrafts—was carried out.
Dean Ninian, Sam M. Dakka
doaj +1 more source
Energy, 2018 In order to investigate the unsteady performance of blunt wind turbine airfoils caused by boundary layer separation and wake eddies, this paper studies the aerodynamic performance by large eddy simulation (LES) and wind tunnel experiment at a Reynolds ...
Guofu Wang, Lei Zhang, W. Shen
semanticscholar +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Aerodynamics of Corrugated Wings: Past, Present, and Future
AerospaceThis paper provides a detailed review of the evolution and development of corrugated wings, a biomimetic concept that is very effective under low Reynolds number flights.
Eduards Lurans +2 more
doaj +1 more source
Aerospace, 2017 This work presents numerical and experimental investigations of an elasto-flexible membrane wing at a Reynolds number of 280,000. Such a concept has the capacity to adapt itself to the incoming flow offering a wider range of the flight envelope.
Julie Piquee, Christian Breitsamter
doaj +1 more source
, 2007 Some insects use leading-edge vortices to generate high lift forces, as has been inferred from qualitative smoke visualisations of the flow around their wings.
Bomphrey, Richard J. +3 more
core +1 more source