Results 51 to 60 of about 6,121,043 (241)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Aerospace, 2017 This work presents numerical and experimental investigations of an elasto-flexible membrane wing at a Reynolds number of 280,000. Such a concept has the capacity to adapt itself to the incoming flow offering a wider range of the flight envelope.
Julie Piquee, Christian Breitsamter
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Aerodynamics of Corrugated Wings: Past, Present, and Future
AerospaceThis paper provides a detailed review of the evolution and development of corrugated wings, a biomimetic concept that is very effective under low Reynolds number flights.
Eduards Lurans +2 more
doaj +1 more source
Leading-Edge Roughness Affecting Diamond-Wing Aerodynamic Characteristics
Aerospace, 2018 Diamond wing configurations for low signature vehicles have been studied in recent years. Yet, despite numerous research on highly swept, sharp edged wings, little research on aerodynamics of semi-slender wings with blunt leading-edges exists. This paper
Andrei Buzica +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A synthesis of hybrid RANS/LES CFD results for F-16XL aircraft aerodynamics
, 2015 A synthesis is presented of recent numerical predictions for the F-16XL aircraft flow fields and aerodynamics. The computational results were all performed with hybrid RANS/LES formulations, with an emphasis on unsteady flows and subsequent aerodynamics,
Tomac, M. +8 more
core +1 more source
Experimental study of blade thickness effects on the global and local performances of a Controlled Vortex Designed axial-flow fan [PDF]
, 2011 The purpose of this work is to study the effects of blade thickness on the performances of an axial-flow fan. Two fans that differ only in the thickness of their blades were studied.
NOURI, Hussain +7 more
core +1 more source