Results 151 to 160 of about 6,369,773 (275)
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019 Introdution: The aim of this study was to investigate the effect of vitamin D supplementation on Klotho levels of the brain tissue. Methods: In this laboratory experimental study, 25 female Lewis rats, after 2 weeks adaptation to lab environmental, were ...
seyedeh fatemeh fatemi +3 more
doaj
Annals of Neurology, Volume 100, Issue 5, Page 915-930, November 2026.Gut wall physiology in multiple sclerosis (MS) and autoimmune neurologic diseases remains underexplored but may span gut barrier dysfunction, enteric glial targeting, mucosal immune dysregulation, and autoimmune targets within the enteric nervous system (ENS).
Federico Montini +4 more
wiley +1 more source
Baicalin reduces the severity of experimental autoimmune encephalomyelitis
Brazilian Journal of Medical and Biological Research, 2007 Scutellaria baicalensis Georgi is one of the important medicinal herbs widely used for the treatment of various inflammatory diseases in Asia. Baicalin (BA) is a bioactive anti-inflammatory flavone found abundantly in Scutellaria baicalensis Georgi.
Y. Zeng +5 more
doaj
Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang +8 more
wiley +1 more source
Immune Regulation by Regnase‐1 and Related Endoribonucleases
European Journal of Immunology, Volume 56, Issue 11, November 2026.Regnase‐1 couples immune signaling to stem‐loop‐mediated mRNA decay. Its biological output depends on cellular and tissue context, determining whether it restrains inflammation, maintains tissue homeostasis, or suppresses inflammation‐associated tumorigenesis.
Takuya Uehata, Osamu Takeuchi
wiley +1 more source
The Maintenance of Dysmyelinated Small‐Diameter Axons by 14‐3‐3s in the Central Nervous System
Glia, Volume 74, Issue 11, November 2026.Dysmyelinated small‐diameter axons are maintained in teneurin‐4 deficient mice at the age of 1 year, while axonal damage is observed. 14‐3‐3s are highly expressed and suppress the progression of the damage in these axons. ABSTRACT In the central nervous system, myelin formed around nerve axons by oligodendrocyte enables efficient conduction of action ...
Nanako Yamada +15 more
wiley +1 more source
The Role of Astrocytes in the Inflammatory Response in Neurodiseases
MedComm, Volume 7, Issue 11, November 2026.Reactive astrocyte‐mediated pathogenic mechanisms in neurodegenerative diseases Schematic representation of key astrocytic pathways contributing to pathology in the pathogenesis of AD, PD, ALS, and HD. In AD, astrocytes exhibit Aβ plaque‐associated activation characterized by GFAP/S100β upregulation, accompanied by impaired EAAT2‐mediated glutamate ...
Shijun Peng +3 more
wiley +1 more source
ALDH2 deficiency exacerbates acrolein-mediated neuropathology in multiple sclerosis
Neural Regeneration ResearchThe pro-inflammatory aldehyde acrolein has long been implicated as a critical factor in the pathology of multiple sclerosis. Given that acrolein can be scavenged via the endogenous enzyme aldehyde dehydrogenase 2 (ALDH2), we sought to investigate whether
Anna Alford +4 more
doaj +1 more source
Experimental Autoimmune Encephalomyelitis (EAE) as Animal Models of Multiple Sclerosis (MS).
Cold Spring Harbor Perspectives in Medicine, 2018 S. Glatigny, E. Bettelli
semanticscholar +1 more source