Results 221 to 230 of about 6,369,773 (275)

Pidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes. [PDF]

BMC Immunol
Wang Y, Zhang S, Li A, Zhao P, Ma X, Zhang X, Wu J, Qiao Z, Wang C, Lang X, Liu X, Sun B, Li H, Liu Y.   +13 more
europepmc   +1 more source

The potential role of S-nitrosoglutathione reductase in astrocyte BAFF expression and B cell activation in experimental autoimmune encephalomyelitis. [PDF]

J Neuroimmunol
Won J, Kim J, Islam SMT, Qiao F, Singh AK, Singh I.   +5 more
europepmc   +1 more source

Siponimod inhibits disease-associated microglia-T cell interactions in chronic experimental autoimmune encephalomyelitis. [PDF]

Acta Neuropathol Commun
Husseini L, Geladaris A, Steinleitner MCJ, Häusler D, Weber MS.   +4 more
europepmc   +1 more source

Depletion of <i>Kif13b</i> promotes neuroinflammatory attack against myelin in an experimental autoimmune encephalomyelitis mouse model. [PDF]

Genes Dis
Chen J, Xu Y, Miao G, Zheng L, Lu K, Zhang W, Huang W, Wang Y, Xian X.   +8 more
europepmc   +1 more source

Impaired T Follicular Regulatory Cell Function and Enhanced T Follicular Helper Cell Activity in Experimental Autoimmune Encephalomyelitis: Mechanistic Insights into CNS Autoimmunity. [PDF]

Int J Mol Sci
Hekimoglu G, Sevgin K, Yucel N, Yesilay G, Erguven SP, Seker M.   +5 more
europepmc   +1 more source

Astrocytic TIA1-Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model. [PDF]

Adv Sci (Weinh)
Fang Z, Hua X, Fan Z, Zhao J, Zhang Y, Zhang Q, Qu X, Pan S, Wan B, Yang S, Li J, Zhang X.   +11 more
europepmc   +1 more source

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Experimental Autoimmune Encephalomyelitis in the Mouse

Current Protocols, 2021
Abstract This article details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP). Additionally, active
Collin, Laaker, Martin, Hsu, Zsuzsanna, Fabry, Stephen D, Miller, William J, Karpus   +4 more
openaire   +2 more sources

Microbiome Methods in Experimental Autoimmune Encephalomyelitis

Current Protocols, 2021
AbstractMicrobiome composition studies are increasingly shedding light on animal models of disease. This paper describes a protocol for analyzing the gut microbiome composition prior to and after the induction of mice to experimental autoimmune encephalomyelitis (EAE), the principal animal model of the human neuroinflammatory demyelinating disease ...
David P, Daberkow, Kristina, Hoffman, Hannah M, Kohl, Tyrel, Long, Trevor O, Kirby, Javier, Ochoa-Repáraz   +5 more
openaire   +2 more sources

Experimental Autoimmune Encephalomyelitis

2004
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system that is induced in laboratory animals by the generation of an immune response against myelin epitopes. It has been used as a prototype of Th1- and/or Th17-driven, organ-specific autoimmunity and as a model for the human disease ...
Praveen, Rao, Benjamin M, Segal
openaire   +4 more sources

Experimental Autoimmune Encephalomyelitis

Revue neurologique, 1998
Experimental autoimmune encephalomyelitis is an induced inflammatory and demyelinating disease of the central nervous system widely used as an animal model for multiple sclerosis. New insights into its pathophysiology have been possible due to recent immunological concepts.
A, Cornet, C, Vizler, R, Liblau
openaire   +3 more sources