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Experimental Approaches to Antifungal Chemotherapy
1981Publisher Summary This chapter discusses the experimental approaches to antifungal chemotherapy. Fungal diseases in general occur in all parts of the world and affect all ages, though a number of particular species are restricted geographically in their incidence. It goes without saying that a systemic fungal infection will require systemic treatment.
J F, Ryley +3 more
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Experimental Rabies Chemotherapy in Mice
American Journal of Veterinary Research, 1971SUMMARY Sixty-five chemical compounds classed according to biological activity were tested in mice to evaluate their therapeutic effect in postexposure rabies treatment. Mice inoculated with lethal doses of rabies virus were treated at the site of viral entry, systemically, or by “blocking” [i.e., injecting the treatment compound between the site of ...
J B, Enright +4 more
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Chemotherapy of experimental echinococcosis
Acta tropica, 1980J, Eckert, B, Burkhardt
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CHEMOTHERAPY IN EXPERIMENTAL TETANUS
The Lancet, 1945D G, EVANS, A T, FULLER, J, WALKER
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The experimental basis for combination chemotherapy
Cancer Treatment Reviews, 1984The basis for combination chemotherapy is not the carefully premeditated interaction of multiple agents which can sometimes be demonstrated to be of benefit in the somewhat artificial mouse tumour systems. The real basis is the uncertainty concerning the sensitivity of the different subpopulations ofcells in the tumour to be treated.
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Implant Chemotherapy of Experimental Filariasis
The American Journal of Tropical Medicine and Hygiene, 1974The in vitro diffusion of the organophosphate famphur from polydimethylsiloxane (PDS) capsules into plasma and their effects on Litomosoides carinii and Dipetalonema witei in jirds was studied. The in vitro rate of diffusion per 24 hours was constant and was directly proportional to the capsule lumen surface area and inversely proportional to the ...
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The American Journal of the Medical Sciences, 1965
R. J. Schnitzer, Frank Hawking
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R. J. Schnitzer, Frank Hawking
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Chemotherapy of experimental echinococcosis in mice
Annals of Tropical Medicine & Parasitology, 1986Mebendazole and flubendazole, administered in food at 500 ppm for 14 consecutive days, had a marked effect on one-year-old hydatid cysts of Echinococcus granulosus in mice infected with protoscolices of human origin. In both treated groups most of the cysts were collapsed compared with none in the controls. A small number of apparently viable cysts was
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