Results 91 to 100 of about 16,072 (215)

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B. [PDF]

, 2018
Disfiguring skin lesions caused by several species of the Leishmania parasite characterize cutaneous leishmaniasis (CL). Successful treatment of CL with intravenous (i.v.) liposomal amphotericin B (LAmB) relies on the presence of adequate antibiotic ...
Alavijeh, Mo, Croft, Simon L, Fortes Francisco, Amanda, Harris, Andy, Murdan, Sudaxshina, Van Bocxlaer, Katrien, Wijnant, Gert-Jan, Yardley, Vanessa   +7 more
core   +2 more sources

Artificial intelligence‐powered microscopy: Transforming the landscape of parasitology

Journal of Microscopy, Volume 301, Issue 2, Page 280-329, February 2026.
Abstract Microscopy and image analysis play a vital role in parasitology research; they are critical for identifying parasitic organisms and elucidating their complex life cycles. Despite major advancements in imaging and analysis, several challenges remain. These include the integration of interdisciplinary data; information derived from various model
Mariana De Niz, Sara Silva Pereira, David Kirchenbuechler, Leandro Lemgruber, Constadina Arvanitis   +4 more
wiley   +1 more source

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S., Konthur, Z., Maslov, D., Simpson, L.   +3 more
core   +1 more source

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

Vox Sanguinis, Volume 121, Issue 2, Page 160-168, February 2026.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima, Suzete Cleusa Ferreira, Anna Shoko Nishiya, Norival Kesper Jr., Jerenice Esdras Ferreira, Claudia Maria de Castro Gomes, Juliana Derriga, Katia Cristina Dantas, Silvia Petrossi Gallo Polato, Nanci Alves Salles, Jose Angelo Lauletta Lindoso, Tila Fanciani, Cesar de Almeida‐Neto, Vanderson Rocha, Alfredo Mendrone Jr.   +14 more
wiley   +1 more source

Leishmania and other intracellular pathogens: selectivity, drug distribution and PK-PD. [PDF]

, 2017
New drugs and treatments for diseases caused by intracellular pathogens, such as leishmaniasis and the Leishmania species, have proved to be some of the most difficult to discover and develop.
Croft, Simon L
core   +1 more source

In Vitro Effect of Methanolic Extract of Quercus infectoria Galls on Promastigotes and Amastigotes of Leishmania major (MRHO/IR/75/ER)

Medical Laboratory Journal, 2018
Background and objectives: Leishmania major is a flagellated parasitic protozoan that causes cutaneous leishmaniasis. Pentavalent antimony compounds are considered the first-line drugs in the treatment of cutaneous leishmaniasis.
Asghar Farghi Yamchi, Mansour Dabirzadeh, Yahya Maroufi   +2 more
doaj  

Experimental cutaneous leishmaniasis: transmission electron microscopy of the inoculation site

International Journal of Experimental Pathology, 1997
Tissue response against inoculation of Leishmania (Leishmania) amazonensis promastigotes in the hind footpad was quite different between two strains of mice: in BALB/c animals there was parasitism of perineurial cells by the 8th week post inoculation (WPI) and heavy parasitism of macrophages, as well as degenerated extracellular parasites close to ...
C, Vasconcellos, M N, Sotto
openaire   +3 more sources

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports
Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies ...
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
doaj   +1 more source

Distribution of putative male sex pheromones among Lutzomyia sandflies (Diptera: Psychodidae).

, 2002
Male Lutzomyia longipalpis produce terpene sex pheromones in glandular tissue underlying the cuticle. The pheromones are transmitted to the surface via cuticle-lined ducts (measuring 0.25 microm in diameter), each of which reaches the surface in the ...
Brazil, RP, Campbell-Lendrum, D, Davies, CR, de Queiroz, RG, Hamilton, JGC, Kelly, DW, Pessoa, FAC   +6 more
core   +1 more source

Effects of qinghaosu (artemisinin) and its derivatives on experimental cutaneous leishmaniasis

Parasitology, 1993
SUMMARYWe have investigated the effect of qinghaosu (QHS, artemisinin) and its derivatives onLeishmania majorreplicationin vitroand on the disease development in mice infected withL. major. Artemisinin is effective against promastigotesin vitro, with an ED50(50% effective dose) at 7.5 × 10−7m.
D M, Yang, F Y, Liew
openaire   +2 more sources