Results 71 to 80 of about 16,072 (215)

Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]

open access: yes, 2017
Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C   +8 more
core   +7 more sources

Arab Medical Tourists in Iran: A Phenomenological Study of Lived Experience

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims This study explores the lived experiences of medical tourists in Shiraz, Iran, a major destination for patients from Arab countries. Understanding these experiences is essential to inform health policy and improve the development of the medical tourism sector. Methods In this phenomenological research which was conducted in
Fatemeh Shaygani   +5 more
wiley   +1 more source

Leishmaniasis in rheumatoid arthritis

open access: yesReumatismo, 2011
Leishmaniasis represents a complex of diseases with an important clinical and epidemiological diversity. Visceral leishmaniasis is of higher priority than cutaneous leishmaniasis as it is a fatal disease in the absence of treatment. The clinical spectrum
M. Cutolo, M.E. Secchi, C. Pizzorni
doaj   +1 more source

Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]

open access: yes, 2017
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines   +7 more
core  

Leishmania Extracellular Vesicles as a Preventive Vaccine Platform Against Leishmaniasis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
The potential of Leishmania‐derived extracellular vesicles (EVs) as a vaccine platform was investigated, emphasizing an affordable, GMP‐compliant production and purification method. Immunization with EV vaccines, either unadjuvanted or combined with α‐galactosylceramide (αGC), induced robust humoral and cellular immune responses, conferring protection ...
Ismail Cem Yilmaz   +24 more
wiley   +1 more source

Nota sobre infecção natural de Oryzomys capito laticeps em foco enzoótico de leishmaniose tegumentar no Estado de São Paulo, Brasil Natural infection of Oryzomys capito laticeps in enzootic focus of cutaneous leishmaniasis in S. Paulo State, Brazil

open access: yesRevista de Saúde Pública, 1973
Assinala-se o isolamento de cepa de Leishmania braziliensis braziliensis em exemplar de Oryzomys capito laticeps capturado em foco enzoótico do Estado de São Paulo, Brasil.
Oswaldo Paulo Forattini   +3 more
doaj   +1 more source

Study of Leishmania pathogenesis in mice : experimental considerations [PDF]

open access: yes, 2015
Although leishmaniases are endemic in 98 countries, they are still considered neglected tropical diseases. Leishmaniases are characterized by the emergence of new virulent and asymptomatic strains of Leishmania spp.
A Asadpour   +65 more
core   +4 more sources

Translational Pharmacokinetic‐Pharmacodynamic Modeling and Efficacious Human Dose Prediction of DNDI‐6148 for the Treatment of Cutaneous Leishmaniasis

open access: yesClinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Cutaneous leishmaniasis is a neglected tropical disease with only one oral treatment option. DNDI‐6148 is an orally bioavailable compound with potent antiparasitic activity in preclinical studies. Establishing skin target‐site pharmacokinetic/pharmacodynamic (PK/PD) relationships is essential to enable its clinical development.
Rasmus Hansen Henninger   +7 more
wiley   +1 more source

Activity of Compounds Isolated From Chilean Lichens Against Experimental Cutaneous Leishmaniasis

open access: yesComparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1997
Three secondary metabolites isolated from Chilean lichens, (+) usnic acid, pannarine and 1'-chloropannarine, were tested against promastigotes forms of three strains of Leishmania ssp. Pannarine and 1'-chloropannarine exhibited in vitro activity at 50 micrograms/ml and (+) usnic acid at 25 micrograms/ml. BALB/c mice infected with Leishmania amazonensis
/Fournet, Alain   +8 more
openaire   +3 more sources

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

open access: yesArchiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi   +17 more
wiley   +1 more source

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