Results 51 to 60 of about 16,072 (215)

Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

npj Vaccines, 2022
Leishmaniasis is a neglected protozoan disease affecting over 12 million people globally with no approved vaccines for human use. New World cutaneous leishmaniasis (CL) caused by L. mexicana is characterized by the development of chronic non-healing skin
Greta Volpedo, Thalia Pacheco-Fernandez, Erin A. Holcomb, Wen-Wei Zhang, Patrick Lypaczewski, Blake Cox, Rebecca Fultz, Chelsea Mishan, Chaitenya Verma, Ryan H. Huston, Abigail R. Wharton, Ranadhir Dey, Subir Karmakar, Steve Oghumu, Shinjiro Hamano, Sreenivas Gannavaram, Hira L. Nakhasi, Greg Matlashewski, Abhay R. Satoskar   +18 more
doaj   +1 more source

Domestic dog ownership in Iran is a risk factor for human infection with Leishmania infantum. [PDF]

, 2002
One explanation proposed for the widespread failure to control zoonotic visceral leishmaniasis by culling infected domestic dogs is that wild canids or humans play significant roles in transmission.
Davies, Clive R, Edrissian, Gholan H, Gavgani, A Samad Mazloumi, Mohebali, Mehdi, Mohite, Hassan   +4 more
core   +1 more source

Infectious Diseases and Antimicrobial Resistance in the Gaza Strip: Epidemiological Drivers, Health System Disruptions, and Global Implications: A Narrative Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims The Gaza Strip has faced prolonged blockade, recurrent military conflicts, and systemic infrastructure collapse since October 2023, resulting in an unprecedented public health crisis characterized by surging infectious diseases and antimicrobial resistance (AMR).
Nima Farhadi, Aref Yarahmadi, Hamed Afkhami   +2 more
wiley   +1 more source

Sex-Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species

Journal of Immunology Research, 2019
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. Leishmania are intracellular parasites that cause disease by suppressing macrophage microbicidal responses.
Ryan D. Lockard, Mary E. Wilson, Nilda E. Rodríguez   +2 more
doaj   +1 more source

Further Evidence of an Association between the Presence of Leishmania RNA Virus 1 and the Mucosal Manifestations in Tegumentary Leishmaniasis Patients. [PDF]

PLoS Neglected Tropical Diseases, 2015
Tegumentary Leishmaniasis (TL) is endemic in Latin America, and Brazil contributes approximately 20 thousand cases per year. The pathogenesis of TL, however, is still not fully understood. Clinical manifestations vary from cutaneous leishmaniasis (CL) to
Lilian Motta Cantanhêde, Cipriano Ferreira da Silva Júnior, Marcos Massayuki Ito, Kátia Paula Felipin, Roberto Nicolete, Juan Miguel Villalobos Salcedo, Renato Porrozzi, Elisa Cupolillo, Ricardo de Godoi Mattos Ferreira   +8 more
doaj   +1 more source

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel, Cardona G, Wilson I, Coa, Juan Carlos, Conesa Milián, Laura, Robledo, Sara M., Upegui Zapata, Yulieth Alexandra, Yepes, Andrés   +6 more
core   +1 more source

Agrarian counterpoint

American Ethnologist, Volume 53, Issue 2, Page 171-182, May 2026.
Abstract In Colombia's northeastern borderlands, agrarian economies shape how disease risk and stigma are understood and managed. As shown in ethnographic fieldwork in and around the Catatumbo region, cutaneous leishmaniasis—a sandfly‐transmitted disease that produces chronic skin lesions—appears in two radically different guises across adjacent ...
Javier Lezaun, Lina Pinto‐García
wiley   +1 more source

Effect of educational intervention based on the PRECEDE-PROCEED model on preventive behaviors of cutaneous leishmaniasis among housewives

Cadernos de Saúde Pública
Leishmaniasis is an endemic disease in Iran. Since education to prevent the disease is important, this study aimed to determine the effect of educational intervention based on the PRECEDE-PROCEED model on preventive behaviors of cutaneous leishmaniosis ...
Ali Khani Jeihooni, Pooyan Afzali Harsini, Seyyed Mansour Kashfi, Tayebe Rakhshani   +3 more
doaj   +1 more source

Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistance

Parasite, 2011
Sitamaquine is a 8-aminoquinoline in development for the treatment of visceral leishmaniasis by oral route, no activity being observed on the experimental cutaneous leishmaniasis experimental models.
Loiseau P.M., Cojean S., Schrével J.
doaj   +1 more source

Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

Frontiers in Immunology, 2014
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; and visceral leishmaniasis, which is fatal if left untreated.
Bruno Mendes Roatt, Bruno Mendes Roatt, Bruno Mendes Roatt, Rodrigo D.O. Aguiar-Soares, Rodrigo D.O. Aguiar-Soares, Wendel eCoura-Vital, Henrique G. Ker, Nádia das Dores Moreira, Juliana eVitoriano-Souza, Rodolfo Cordeiro Giunchetti, Rodolfo Cordeiro Giunchetti, Cláudia Martins Carneiro, Alexandre Barbosa Reis, Alexandre Barbosa Reis, Alexandre Barbosa Reis   +14 more
doaj   +1 more source