Results 51 to 60 of about 6,030,066 (175)

Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg, Dennis Wienand, Lucie Harpain, Marie‐Luise Brunner‐Kovarik, Julia Walochnik, Markus Wiesmueller, Amélie Hampel, Tibor Spath, Lukas Trnka, Judit Simon, Alessandra Handisurya   +10 more
wiley   +1 more source

Effect of educational intervention based on the PRECEDE-PROCEED model on preventive behaviors of cutaneous leishmaniasis among housewives

Cadernos de Saúde Pública
Leishmaniasis is an endemic disease in Iran. Since education to prevent the disease is important, this study aimed to determine the effect of educational intervention based on the PRECEDE-PROCEED model on preventive behaviors of cutaneous leishmaniosis ...
Ali Khani Jeihooni, Pooyan Afzali Harsini, Seyyed Mansour Kashfi, Tayebe Rakhshani   +3 more
doaj   +1 more source

Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistance

Parasite, 2011
Sitamaquine is a 8-aminoquinoline in development for the treatment of visceral leishmaniasis by oral route, no activity being observed on the experimental cutaneous leishmaniasis experimental models.
Loiseau P.M., Cojean S., Schrével J.
doaj   +1 more source

Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis

npj Vaccines, 2022
Leishmaniasis is a neglected protozoan disease affecting over 12 million people globally with no approved vaccines for human use. New World cutaneous leishmaniasis (CL) caused by L. mexicana is characterized by the development of chronic non-healing skin
Greta Volpedo, Thalia Pacheco-Fernandez, Erin A. Holcomb, Wen-Wei Zhang, Patrick Lypaczewski, Blake Cox, Rebecca Fultz, Chelsea Mishan, Chaitenya Verma, Ryan H. Huston, Abigail R. Wharton, Ranadhir Dey, Subir Karmakar, Steve Oghumu, Shinjiro Hamano, Sreenivas Gannavaram, Hira L. Nakhasi, Greg Matlashewski, Abhay R. Satoskar   +18 more
doaj   +1 more source

Symmetrical Lupoid Onychodystrophy in Review: Lessons Learned From 31 Cases

Veterinary Dermatology, EarlyView.
Background: Symmetrical lupoid onychodystrophy (SLO) is a complex disease that exclusively affects the claws of dogs and represents a therapeutic challenge. Biopsy sampling of the third phalanx for histopathological evaluation has historically been the recommended diagnostic test, yet clinical diagnosis is currently encouraged.
Jessica R. Calesso, Clarissa P. Souza, Stephanie R. Bruner, Adriane P. C. V. Bicalho   +3 more
wiley   +1 more source

Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

Frontiers in Immunology, 2014
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; and visceral leishmaniasis, which is fatal if left untreated.
Bruno Mendes Roatt, Bruno Mendes Roatt, Bruno Mendes Roatt, Rodrigo D.O. Aguiar-Soares, Rodrigo D.O. Aguiar-Soares, Wendel eCoura-Vital, Henrique G. Ker, Nádia das Dores Moreira, Juliana eVitoriano-Souza, Rodolfo Cordeiro Giunchetti, Rodolfo Cordeiro Giunchetti, Cláudia Martins Carneiro, Alexandre Barbosa Reis, Alexandre Barbosa Reis, Alexandre Barbosa Reis   +14 more
doaj   +1 more source

Further Evidence of an Association between the Presence of Leishmania RNA Virus 1 and the Mucosal Manifestations in Tegumentary Leishmaniasis Patients. [PDF]

PLoS Neglected Tropical Diseases, 2015
Tegumentary Leishmaniasis (TL) is endemic in Latin America, and Brazil contributes approximately 20 thousand cases per year. The pathogenesis of TL, however, is still not fully understood. Clinical manifestations vary from cutaneous leishmaniasis (CL) to
Lilian Motta Cantanhêde, Cipriano Ferreira da Silva Júnior, Marcos Massayuki Ito, Kátia Paula Felipin, Roberto Nicolete, Juan Miguel Villalobos Salcedo, Renato Porrozzi, Elisa Cupolillo, Ricardo de Godoi Mattos Ferreira   +8 more
doaj   +1 more source

Natural Infection by Toscana Virus and Other Phleboviruses in Wild Sand Flies From Spain: Prevalence, Genetic Characterization and Tripartite Interactions With Leishmania infantum and Wolbachia

Zoonoses and Public Health, Volume 73, Issue 7, Page 655-669, November 2026.
ABSTRACT Introduction Toscana virus (TOSV) and Leishmania species are sand fly‐borne pathogens that pose a significant public health threat and an increasing risk of exposure in Europe. The objective of this study was to identify the phleboviruses circulating in an area endemic for sand fly‐borne pathogens and to estimate infection prevalence in wild ...
Andrés Torres‐Llamas, Antonio Sampedro, Victoriano Díaz‐Sáez, Manuel Morales‐Yuste, Javier Rodríguez‐Granger, Irene Pedrosa‐Corral, José María Navarro‐Marí, Francisco Morillas‐Márquez, Joaquina Martín‐Sánchez   +8 more
wiley   +1 more source

Advances in leishmaniasis.

, 2005
Governed by parasite and host factors and immunoinflammatory responses, the clinical spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions), and disseminated infection (cutaneous, mucosal, or visceral).
Berman, Jonathan D, Murray, Henry W, Davies, Clive R, Saravia, Nancy G   +3 more
core   +1 more source

Formulation of Amphotericin B in PEGylated Liposomes for Improved Treatment of Cutaneous Leishmaniasis by Parenteral and Oral Routes

Pharmaceutics, 2022
Liposomal amphotericin B (AmB) or AmBisome® is the most effective and safe therapeutic agent for visceral leishmaniasis (VL), but its clinical efficacy is limited in cutaneous leishmaniasis (CL) and HIV/VL co-infection.
Guilherme S. Ramos, Virgínia M. R. Vallejos, Gabriel S. M. Borges, Raquel M. Almeida, Izabela M. Alves, Marta M. G. Aguiar, Christian Fernandes, Pedro P. G. Guimarães, Ricardo T. Fujiwara, Philippe M. Loiseau, Lucas A. M. Ferreira, Frédéric Frézard   +11 more
doaj   +1 more source