Results 31 to 40 of about 16,072 (215)

Healed Lesions of Human Cutaneous Leishmaniasis Caused By Leishmania major Do Not Shelter Persistent Residual Parasites

Frontiers in Cellular and Infection Microbiology, 2022
In human cutaneous leishmaniasis (HCL) caused by Leishmania (L.) major, the cutaneous lesions heal spontaneously and induce a Th1-type immunity that confers solid protection against reinfection.
Rabiaa M. Sghaier, Rabiaa M. Sghaier, Fouad Benhnini, Fouad Benhnini, Fatma Z. Guerfali, Fatma Z. Guerfali, Hanène Attia, Hanène Attia, Aymen Bali, Aymen Bali, Amor Zaatour, Amor Zaatour, Amor Zaatour, Ghada Mkannez, Ghada Mkannez, Adel Gharbi, Adel Gharbi, Adel Gharbi, Nabil Belhaj-Hamida, Nabil Belhaj-Hamida, Nabil Belhaj-Hamida, Hichem Dridi, Hichem Dridi, Hichem Dridi, Afif Ben-Salah, Afif Ben-Salah, Afif Ben-Salah, Afif Ben-Salah, Koussay Dellagi, Koussay Dellagi, Dhafer Laouini, Dhafer Laouini   +31 more
doaj   +1 more source

Chemotherapeutic potential of 17-AAG against cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis. [PDF]

PLoS Neglected Tropical Diseases, 2014
BACKGROUND: Leishmaniasis remains a worldwide public health problem. The limited therapeutic options, drug toxicity and reports of resistance, reinforce the need for the development of new treatment options.
Diego M Santos, Antonio L O A Petersen, Fabiana S Celes, Valeria M Borges, Patricia S T Veras, Camila I de Oliveira   +5 more
doaj   +1 more source

Emerging and Re-Emerging Zoonoses of Dogs and Cats. [PDF]

, 2014
Since the middle of the 20th century, pets are more frequently considered as "family members" within households. However, cats and dogs still can be a source of human infection by various zoonotic pathogens.
Chomel, Bruno B
core   +2 more sources

Protective Immunity and Vaccination Against Cutaneous Leishmaniasis

Frontiers in Immunology, 2012
Although a great deal of knowledge has been gained from studies on the immunobiology of leishmaniasis, there is still no effective vaccine against the disease.
Ifeoma eOkwor, Zhirong eMou, Liu eDong, JUDE EZEH UZONNA, JUDE EZEH UZONNA   +4 more
doaj   +1 more source

Combination therapy with tamoxifen and amphotericin B in experimental cutaneous leishmaniasis. [PDF]

Antimicrob Agents Chemother, 2014
ABSTRACTLeishmaniasis chemotherapy remains very challenging. The high cost of active drugs, along with the severity of their side effects and the increasing failure rate of the current therapeutic schemes, calls for the discovery of new active drugs and schemes of treatment.
Trinconi CT, Reimão JQ, Yokoyama-Yasunaka JK, Miguel DC, Uliana SR.   +4 more
europepmc   +4 more sources

Treatment of experimental cutaneous leishmaniasis with liposome-intercalated amphotericin B [PDF]

Antimicrobial Agents and Chemotherapy, 1984
The therapeutic efficacy of a liposomal preparation of amphotericin B was evaluated in two murine models of cutaneous leishmaniasis. No significant decrease in tissue parasite density was observed in C57BL/6 mice after systemic treatment instituted seven days after footpad inoculation with Leishmania tropica; in contrast, BALB/c mice showed a modest ...
C B, Panosian, M, Barza, F, Szoka, D J, Wyler   +3 more
openaire   +2 more sources

Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement [PDF]

, 1990
Nine patients who became diabetic after upper-abdominal exenteration and liver transplantation were given pancreatic islet-cell grafts obtained from the liver donor (eight cases), a third-party donor (one), or both (four). Two patients were diabetic when
Alejandro, R, Demetris, AJ, Fung, JJ, Mintz, DH, Ricordi, C, Starzl, TE, Todo, S, Tzakis, AG, Zeng, Y   +8 more
core   +1 more source

Insights on adaptive and innate immunity in canine leishmaniosis [PDF]

, 2016
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a systemic disease, which can present with variable clinical signs, and clinicopathological abnormalities.
Abi Abdallah, Alexander, Catchpole, DAMER P. BLAKE, de Souza Carmo, Green, Kensil, LAIA SOLANO-GALLEGO, Lopez, Margarito, Ordeix, Pinelli, Pitta, Quinnell, Sadick, Sanchez, SHAZIA HOSEIN, Silva, Vouldoukis, Wakelin   +19 more
core   +4 more sources

Differential Susceptibility to Antimony in Strains and Clinical Isolates of Leishmania amazonensis from Brazil: In Vitro and In Vivo Studies and Implications for Drug Response and Treatment Failure

Pathogens
In Brazil, cutaneous leishmaniasis is endemic and may be caused by Leishmania amazonensis. This species is the second most prevalent species in that country, and it is responsible for localized cutaneous and diffuse cutaneous leishmaniasis.
Victor de Sousa Agostino, Leonardo F. Geres, Stéphane de la Roca, Beatriz T. de Moraes, Juliana I. Aoki, Elizabeth M. Coser, Nilson Branco, Adriano C. Coelho   +7 more
doaj   +1 more source

The TLR2/6 ligand PAM2CSK4 is a Th2 polarizing adjuvant in Leishmania major and Brugia malayi murine vaccine models. [PDF]

, 2016
Toll-like receptors (TLRs) play an important role in the innate and adaptive immune responses to pathogens, and are the target of new vaccine adjuvants.
Bates, PA, Guimarães, A, Halliday, A, Taylor, MJ, Turner, JD   +4 more
core   +7 more sources