Results 21 to 30 of about 8,397 (218)

Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Mesocricetus auratus) with formulations containing pentamidine [PDF]

Acta Amazonica, 2017
Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration.
Claudia Dantas COMANDOLLI-WYREPKOWSKI, Iryna GRAFOVA, Maricleide de Farias NAIFF, Maurizio AVELLA, Gennaro GENTILE, Andriy GRAFOV, Antonia Maria Ramos FRANCO   +6 more
doaj   +2 more sources

Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis

Pathogens, 2020
Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In leishmaniasis, UA killed different species of parasites, and it was active in the experimental model of cutaneous and visceral leishmaniasis.
Jéssica Adriana Jesus, Thays Nicolli Fragoso da Silva, Eduardo Seiji Yamamoto, João Henrique G. Lago, Márcia Dalastra Laurenti, Luiz Felipe Domingues Passero   +5 more
doaj   +1 more source

Leishmaniasis: new approaches to disease control. [PDF]

, 2003
The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L, Sundar, Shyam, Davies, Clive R., Croft, Simon L., Kaye, Paul, Davies, Clive R   +5 more
core   +1 more source

Indoor and peridomestic transmission of American cutaneous leishmaniasis in northwestern Argentina: a retrospective case-control study. [PDF]

, 2003
A case-control study was carried out during 1990-1994 to identify risk factors associated with American cutaneous leishmaniasis (ACL) in Santiago del Estero, Argentina.
Quigley, Maria A, Yadon, ZE, A. Quigley, MARIA A. QUIGLEY, Yadon, Zaida E, Quigley, MA, Rodrigues, LC, Davies, CR, Laura C. Rodrigues, Davies, Clive R, Zaida E. Yadon, Quigley, Maria, Clive R. Davies, Rodrigues, Laura C, Maria   +14 more
core   +1 more source

Short communication: The cost-effectiveness of cutaneous leishmaniasis patient management during an epidemic in Chaparral, Colombia in 2004. [PDF]

, 2007
We calculated ranges for the cost per disability adjusted life year (DALY) averted for cutaneous leishmaniasis (CL) treatment during an ongoing epidemic of CL in Chaparral, Colombia.
Mercedes Del Pilar Mahecha, Juan Carlos Vega, Del Pilar Mahecha, Mercedes, Vega, Juan Carlos, Reithinger, Richard, Ángela Rocío Baron, Rafael Montaña, Montaña, Rafael, Sanchez, Boris Fernando, Montero, Luz Mery, Baron, Angela Rocío, Boris Fernando Sanchez, Bladimir Dueñes, Richard Reithinger, Luz Mery Montero, Dueñes, Bladimir   +15 more
core   +1 more source

BODY WEIGHT AS A DETERMINANT OF CLINICAL EVOLUTION IN HAMSTERS (Mesocricetus auratus) INFECTED WITH Leishmania (Viannia) panamensis

Revista do Instituto de Medicina Tropical de São Paulo, 2013
SUMMARY The clinical outcome of infection with Leishmania species of the subgenus Viannia in hamster model (Mesocricetus auratus) has shown to be different depending on experimental protocol.
Angela Maria Gomez-Galindo, Lucy Gabriela Delgado-Murcia   +1 more
doaj   +1 more source

Age-related alteration of arginase activity impacts on severity of leishmaniasis. [PDF]

, 2008
BACKGROUND: The leishmaniases are a group of vector-borne parasitic diseases that represent a major international public health problem; they belong to the most neglected tropical diseases and have one of the highest rates of morbidity and mortality. The
Asrat Hailu, Choi, B., Abebe, T, Munder, Markus, Choi, B-S, Abebe Tamrat, Modolell, M, Choi Beak-San, Manuel Modolell, Hailu, A, Abebe, T., Fuentes, J., Modolell Manuel, Kropf Pascale, Abebe, Tamrat, Munder, M, Ingrid Müller, Kropf, P, Müller, Ingrid, Markus Munder, Modolell, M., Munder, M., Kropf, P., Kropf, Pascale, Beak-San Choi, Hailu, A., Fuentes, Jose M, Munder Markus, Fuentes Jose M., Pascale Kropf, Muller, I, Fuentes, JM, Jose M. Fuentes, Müller Ingrid, Jose M Fuentes, Hailu Asrat, Choi, Beak-San, Hailu, Asrat, Modolell, Manuel, Müller, I., Tamrat Abebe   +40 more
core   +1 more source

Advances in leishmaniasis. [PDF]

, 2005
Governed by parasite and host factors and immunoinflammatory responses, the clinical spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions), and disseminated infection (cutaneous, mucosal, or visceral).
Berman, Jonathan D, Murray, Henry W, Davies, Clive R, Saravia, Nancy G   +3 more
core   +1 more source

Radical Cure of Experimental Cutaneous Leishmaniasis by the Bisphosphonate Pamidronate [PDF]

The Journal of Infectious Diseases, 2002
The effects in vivo of the bisphosphonate drug pamidronate, used in bone resorption therapy, were investigated in an experimental model of cutaneous leishmaniasis. Pamidronate at an intraperitoneal dose of 10 mg/kg/day for 5 days effects a radical cure of cutaneous leishmaniasis in Balb/c mice, as evidenced by long-term disappearance of lesions ...
Noris, Rodriguez, Brian N, Bailey, Michael B, Martin, Eric, Oldfield, Julio A, Urbina, Roberto, Docampo   +5 more
openaire   +2 more sources

The efficacy of thermotherapy to treat cutaneous leishmaniasis in Colombia: a comparative observational study in an operational setting. [PDF]

, 2009
An open label, comparative study to compare the efficacy of thermotherapy to meglumine antimoniate in treating cutaneous leishmaniasis patients in an operational context was carried out in Chaparral, Colombia.
Reithinger, Richard, Sánchez Polania, Boris Fernando, Mahecha, Mercedes del Pilar, Montaña, Rafael, Sanchez, Boris Fernando, Montero, Luz Mery, Baron, Angela Rocío, Vega, Juan Carlos, Dueñes, Bladimir   +8 more
core   +1 more source