Results 1 to 10 of about 7,418 (172)

Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis [PDF]

open access: yesJournal of Immunology Research, 2021
The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. Such enzymes can be blocked by azoles and allylamines drugs, such as the antifungal butenafine chloride.
Adriana Bezerra-Souza   +5 more
doaj   +9 more sources

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis [PDF]

open access: yesMolecules, 2020
Chitosan nanoparticles have gained attention as drug delivery systems (DDS) in the medical field as they are both biodegradable and biocompatible with reported antimicrobial and anti-leishmanial activities.
Alaa Riezk   +4 more
doaj   +4 more sources

Immunomodulation From Moderate Exercise Promotes Control of Experimental Cutaneous Leishmaniasis [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Physical exercise has been described as an important tool in the prevention and treatment of numerous diseases as it promotes a range of responses and adaptations in several biological systems, including the immune system.
Rodrigo Terra   +7 more
doaj   +2 more sources

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis. [PDF]

open access: yesInt J Parasitol Drugs Drug Resist, 2019
Van Bocxlaer K   +11 more
europepmc   +2 more sources

Microemulsion based on methyl 3,4,5-trihydroxybenzoate for the topical treatment of cutaneous leishmaniasis: an in vivo assay [PDF]

open access: yesActa Amazonica, 2023
Cutaneous leishmaniasis, caused by protozoa of the genus Leishmania, presents diverse clinical manifestations, and current therapeutic options have limitations, including long treatment periods, potential hospitalization, and excessive pain during ...
Thiago de Jesus BACHA   +8 more
doaj   +1 more source

Development of a biocompatible polymeric chitosan system for the release of compounds with leishmanicidal activity

open access: yesMaterials & Design, 2021
Leishmaniasis is a tropical disease caused by parasites of the genus Leishmania spp; it presents different clinical manifestations, of which cutaneous leishmaniasis is the most common form, and it is endemic in more than 70 countries worldwide. Only four
Jorge Higuita-Castro   +6 more
doaj   +1 more source

Activity of paromomycin against Leishmania amazonensis: Direct correlation between susceptibility in vitro and the treatment outcome in vivo

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2020
Paromomycin is an aminoglycoside antibiotic approved in 2006 for the treatment of visceral leishmaniasis caused by Leishmania donovani in Southeast Asia.
Elizabeth M. Coser   +5 more
doaj   +1 more source

A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L.
Adriano C Coelho   +5 more
doaj   +1 more source

Role of magnetic Field in the Healing of Cutaneous Leishmaniasis Lesions in Mice [PDF]

open access: yesArchives of Razi Institute, 2020
Leishmaniasisis an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease.
M. Dastgheib   +4 more
doaj   +1 more source

Cutaneous leishmaniasis and pregnancy

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
We studied a 19-year-old woman, with a 4-month pregnancy who presented with four cutaneous leg ulcers of three months of evolution diagnosed by biopsy as cutaneous leishmaniasis. Direct smear and the leishmanin skin test were negative.
Ángel Jaimes, Gerzaín Rodríguez
doaj   +1 more source

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