Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneous Leishmaniasis [PDF]
The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. Such enzymes can be blocked by azoles and allylamines drugs, such as the antifungal butenafine chloride.
Adriana Bezerra-Souza +5 more
doaj +9 more sources
Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis [PDF]
Chitosan nanoparticles have gained attention as drug delivery systems (DDS) in the medical field as they are both biodegradable and biocompatible with reported antimicrobial and anti-leishmanial activities.
Alaa Riezk +4 more
doaj +4 more sources
Immunomodulation From Moderate Exercise Promotes Control of Experimental Cutaneous Leishmaniasis [PDF]
Physical exercise has been described as an important tool in the prevention and treatment of numerous diseases as it promotes a range of responses and adaptations in several biological systems, including the immune system.
Rodrigo Terra +7 more
doaj +2 more sources
Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis. [PDF]
Van Bocxlaer K +11 more
europepmc +2 more sources
Microemulsion based on methyl 3,4,5-trihydroxybenzoate for the topical treatment of cutaneous leishmaniasis: an in vivo assay [PDF]
Cutaneous leishmaniasis, caused by protozoa of the genus Leishmania, presents diverse clinical manifestations, and current therapeutic options have limitations, including long treatment periods, potential hospitalization, and excessive pain during ...
Thiago de Jesus BACHA +8 more
doaj +1 more source
Leishmaniasis is a tropical disease caused by parasites of the genus Leishmania spp; it presents different clinical manifestations, of which cutaneous leishmaniasis is the most common form, and it is endemic in more than 70 countries worldwide. Only four
Jorge Higuita-Castro +6 more
doaj +1 more source
Paromomycin is an aminoglycoside antibiotic approved in 2006 for the treatment of visceral leishmaniasis caused by Leishmania donovani in Southeast Asia.
Elizabeth M. Coser +5 more
doaj +1 more source
A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome. [PDF]
Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L.
Adriano C Coelho +5 more
doaj +1 more source
Role of magnetic Field in the Healing of Cutaneous Leishmaniasis Lesions in Mice [PDF]
Leishmaniasisis an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease.
M. Dastgheib +4 more
doaj +1 more source
Cutaneous leishmaniasis and pregnancy
We studied a 19-year-old woman, with a 4-month pregnancy who presented with four cutaneous leg ulcers of three months of evolution diagnosed by biopsy as cutaneous leishmaniasis. Direct smear and the leishmanin skin test were negative.
Ángel Jaimes, Gerzaín Rodríguez
doaj +1 more source

