Results 11 to 20 of about 8,397 (218)

Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2012
BackgroundCutaneous leishmaniasis is a vector-borne disease that is in Ethiopia mainly caused by the parasite Leishmania aethiopica. This neglected tropical disease is common in rural areas and causes serious morbidity.
Tamrat Abebe   +13 more
doaj   +2 more sources

Cutaneous leishmaniasis and pregnancy [PDF]

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2018
We studied a 19-year-old woman, with a 4-month pregnancy who presented with four cutaneous leg ulcers of three months of evolution diagnosed by biopsy as cutaneous leishmaniasis. Direct smear and the leishmanin skin test were negative.
Ángel Jaimes, Gerzaín Rodríguez
doaj   +3 more sources

Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer. [PDF]

open access: yesImmunology
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Barros ABB   +5 more
europepmc   +2 more sources

American cutaneous leishmaniasis in domestic dogs: an example of the use of the polymerase chain reaction for mass screening in epidemiological studies. [PDF]

open access: yes, 2002
Domestic dogs (Canis familiaris) are firmly incriminated as reservoir hosts of zoonotic visceral leishmaniasis. As an increasing number of studies have reported high infection rates with American cutaneous leishmaniasis (ACL) in dogs, it is suggested ...
Reithinger, R, Davies, CR
core   +7 more sources

Brain Involvement in Leishmaniasis. [PDF]

open access: yesCell Biochem Funct
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS   +2 more
europepmc   +2 more sources

Activity of paromomycin against Leishmania amazonensis: Direct correlation between susceptibility in vitro and the treatment outcome in vivo

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2020
Paromomycin is an aminoglycoside antibiotic approved in 2006 for the treatment of visceral leishmaniasis caused by Leishmania donovani in Southeast Asia.
Elizabeth M. Coser   +5 more
doaj   +1 more source

A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2016
Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L.
Adriano C Coelho   +5 more
doaj   +1 more source

Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review. [PDF]

open access: yesChem Biol Drug Des
This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
da Veiga Oliveira ME   +3 more
europepmc   +2 more sources

Role of magnetic Field in the Healing of Cutaneous Leishmaniasis Lesions in Mice [PDF]

open access: yesArchives of Razi Institute, 2020
Leishmaniasisis an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease.
M. Dastgheib   +4 more
doaj   +1 more source

Cutaneous leishmaniasis. [PDF]

open access: yes, 2007
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a group of diseases because of the varied spectrum of clinical manifestations, which range from small cutaneous nodules to gross mucosal tissue destruction ...
Claude Pirmez   +17 more
core   +1 more source

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