Efficacy of oleylphosphocholine in experimental cutaneous leishmaniasis. [PDF]
J Antimicrob Chemother, 2023 Abstract Objectives Cutaneous leishmaniasis (CL) is a neglected tropical disease causing a range of skin lesions for which safe and efficacious drugs are lacking. Oleylphosphocholine (OLPC) is structurally similar to miltefosine and has previously demonstrated potent activity against visceral ...
Van Bocxlaer K +8 more
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CD4+ T cell subsets in experimental cutaneous leishmaniasis [PDF]
Memorias do Instituto Oswaldo Cruz, 1988 Phillip Scott +4 more
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INFLUENCE OF MICROBIOTA IN EXPERIMENTAL CUTANEOUS LEISHMANIASIS IN SWISS MICE [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1999 Infection of Swiss/NIH mice with Leishmania major was compared with infection in isogenic resistant C57BL/6 and susceptible BALB/c mice. Swiss/NIH mice showed self-controlled lesions in the injected foot pad. The production of high levels of interferon-g
OLIVEIRA Marcia Rosa de +5 more
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Brain Involvement in Leishmaniasis. [PDF]
Cell Biochem FunctABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS +2 more
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A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome. [PDF]
PLoS Neglected Tropical Diseases, 2016 Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L.
Adriano C Coelho +5 more
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Role of magnetic Field in the Healing of Cutaneous Leishmaniasis Lesions in Mice [PDF]
Archives of Razi Institute, 2020 Leishmaniasisis an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease.
M. Dastgheib +4 more
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Leishmaniasis: new approaches to disease control. [PDF]
, 2003 The leishmaniases afflict the world's poorest populations. Among the two million new cases each year in the 88 countries where the disease is endemic (fig 1), it is estimated that 80% earn less than $2 a day.
Croft, Simon L +3 more
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Cutaneous leishmaniasis and pregnancy
Biomédica: revista del Instituto Nacional de Salud, 2018 We studied a 19-year-old woman, with a 4-month pregnancy who presented with four cutaneous leg ulcers of three months of evolution diagnosed by biopsy as cutaneous leishmaniasis. Direct smear and the leishmanin skin test were negative.
Ángel Jaimes, Gerzaín Rodríguez
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Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Mesocricetus auratus) with formulations containing pentamidine [PDF]
Acta Amazonica, 2017 Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration.
Claudia Dantas COMANDOLLI-WYREPKOWSKI +6 more
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Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis
Pathogens, 2020 Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In leishmaniasis, UA killed different species of parasites, and it was active in the experimental model of cutaneous and visceral leishmaniasis.
Jéssica Adriana Jesus +5 more
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