Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia. [PDF]
BackgroundCutaneous leishmaniasis is a vector-borne disease that is in Ethiopia mainly caused by the parasite Leishmania aethiopica. This neglected tropical disease is common in rural areas and causes serious morbidity.
Tamrat Abebe +13 more
doaj +2 more sources
Cutaneous leishmaniasis and pregnancy [PDF]
We studied a 19-year-old woman, with a 4-month pregnancy who presented with four cutaneous leg ulcers of three months of evolution diagnosed by biopsy as cutaneous leishmaniasis. Direct smear and the leishmanin skin test were negative.
Ángel Jaimes, Gerzaín Rodríguez
doaj +3 more sources
Thymus and Leishmania at the Crossroads: Autoimmunity and Cancer. [PDF]
Conceptual ‘Crossroads Model’ linking Leishmania, thymic infection and immune dysregulation: an integrative model is proposed in which Leishmania infection disrupts thymic architecture and stromal–thymocyte interactions. These alterations converge to promote defective tolerance, increased autoimmune risk and a microenvironment permissive to malignant ...
Barros ABB +5 more
europepmc +2 more sources
American cutaneous leishmaniasis in domestic dogs: an example of the use of the polymerase chain reaction for mass screening in epidemiological studies. [PDF]
Domestic dogs (Canis familiaris) are firmly incriminated as reservoir hosts of zoonotic visceral leishmaniasis. As an increasing number of studies have reported high infection rates with American cutaneous leishmaniasis (ACL) in dogs, it is suggested ...
Reithinger, R, Davies, CR
core +7 more sources
Brain Involvement in Leishmaniasis. [PDF]
ABSTRACT Leishmaniasis is a neglected tropical disease caused by infection with the protozoan parasite Leishmania and it is a significant global health problem. The disease has a wide clinical spectrum, from tegumentary leishmaniasis (TL) that encompasses cutaneous (CL), mucosal (ML) and cutaneous‐diffuse (CDL) forms, to the potentially fatal systemic ...
Freitas CS +2 more
europepmc +2 more sources
Paromomycin is an aminoglycoside antibiotic approved in 2006 for the treatment of visceral leishmaniasis caused by Leishmania donovani in Southeast Asia.
Elizabeth M. Coser +5 more
doaj +1 more source
A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome. [PDF]
Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L.
Adriano C Coelho +5 more
doaj +1 more source
Peptides as a Therapeutic Alternative Against Leishmaniasis: A Scoping Review. [PDF]
This scoping review of 79 studies identified 231 antimicrobial peptides with anti‐Leishmania activity, including natural‐derived and synthetic peptides (inspired by natural sources or developed through rational design). Most were evaluated in vitro against promastigote and/or amastigote forms, with synthetic peptides showing a more promising effect ...
da Veiga Oliveira ME +3 more
europepmc +2 more sources
Role of magnetic Field in the Healing of Cutaneous Leishmaniasis Lesions in Mice [PDF]
Leishmaniasisis an important tropical cutaneous disease that is endemic in the Middle East, including Iran. There is no consensus on the appropriate therapeutic method, dose, and duration for this disease.
M. Dastgheib +4 more
doaj +1 more source
Cutaneous leishmaniasis. [PDF]
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a group of diseases because of the varied spectrum of clinical manifestations, which range from small cutaneous nodules to gross mucosal tissue destruction ...
Claude Pirmez +17 more
core +1 more source

