Results 41 to 50 of about 16,072 (215)

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]

, 1990
BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS, Heinzel, FP, Holaday, BJ, Locksley, RM, Pu, RT, Sadick, MD   +5 more
core   +1 more source

The Effectiveness of Perovskia abrotanoides Extract Topical Formulation on the Cutaneous Leishmaniasis: A Randomized Controlled Clinical Trial

Journal of Research in Pharmacy Practice
Objective: Despite many attempts to treat leishmaniasis, new approaches are necessary to reduce the burden of disease. Perovskia abrotanoides (Brazambel) has shown significant effects against Leishmania parasites in some studies.
Maryam Sadat Tayebi, Nazila Poostiyan, Masoud Sadeghi Dinani, Erfaneh Ghassami, Rasool Soltani   +4 more
doaj   +1 more source

Limited Activity Of Miltefosine In Murine Models Of Cryptococcal Meningoencephalitis And Disseminated Cryptococcosis [PDF]

, 2013
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections.
Bocanegra, Rosie, Kirkpatrick, William R., Najvar, Laura K., Patterson, Thomas F., Sorrell, Tania C., Wiederhold, Nathan P.   +5 more
core   +1 more source

Exposure of phosphatidylserine on Leishmania amazonensis isolates is associated with diffuse cutaneous leishmaniasis and parasite infectivity. [PDF]

PLoS ONE, 2012
Diffuse cutaneous leishmaniasis (DCL) is a rare clinical manifestation of leishmaniasis, characterized by an inefficient parasite-specific cellular response and heavily parasitized macrophages.
Jaqueline França-Costa, João Luiz Mendes Wanderley, Poliana Deolindo, Jessica B Zarattini, Jackson Costa, Lynn Soong, Marcello André Barcinski, Aldina Barral, Valeria M Borges   +8 more
doaj   +1 more source

Genetic, serological and biochemical characterization of Leishmania tropica from foci in northern Palestine and discovery of zymodeme MON-307 [PDF]

, 2012
Background Many cases of cutaneous leishmaniasis (CL) have been recorded in the Jenin District based on their clinical appearance. Here, their parasites have been characterized in depth.
A Al-Jawabreh, A Al-Jawabreh, A Al-Jawabreh, A Warburg, Abedelmajeed Nasereddin, Christophe Ravel, CL Eisenberger, CL Jaffe, DE Dobson, DF Smith, E Cupolillo, EK Saliba, EK Saliba, F Pratlong, Fouad El Baidouri, Francine Pratlong, G Anders, G Schonian, G Schonian, Gabriele Schonian, IL Mauricio, J Felsenstein, JA Rioux, JA Rioux, Jean-Pierre Dedet, JM Schwenkenbecher, K Azmi, K Azmi, Kifaya Azmi, LF Schnur, LF Schnur, LF Schnur, LF Schnur, Lionel Schnur, M Rhajaoui, M Svobodova, MZ Alam, R Maazoun, RL Jacobson, RP Soares, S Adler, S Kamhawi, S Martinez-Calvillo, SM Le Blancq, SM Le Blancq, Suheir Ereqat, Y Schlein, Y Schlein, Ziad Abdeen   +48 more
core   +3 more sources

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Antileishmanial activity of extracts from Libidibia ferrea: development of in vitro and in vivo tests [PDF]

Acta Amazonica, 2017
Treatment of cutaneous leishmaniasis (CL) is difficult due to the scarce number of drugs able to eliminate completely the intracellular form of the parasite.
Claudia Dantas COMANDOLLI-WYREPKOWSKI, Bruno Bezerra JENSEN, Iryna GRAFOVA, Pierre Alexandre dos SANTOS, Angela Maria Comapa BARROS, Fabiane Veloso SOARES, José Fernando Marques BARCELLOS, Aline Fagundes da SILVA, Andriy GRAFOV, Antonia Maria Ramos FRANCO   +9 more
doaj   +2 more sources

Adjustment and Completion of BASNEF Model to Provide a New Model for Educating Large Populations in Relation to Cutaneous Leishmaniasis [PDF]

, 2014
Background: Educational models that have been created for educating small populations do not have enough efficacy for educating large populations, so based on this premise and also high prevalence of Cutaneous Leishmaniasis (CL) in the Islamic Republic
Behravesh, O., Ghanbari, M.R., Hasanzadeh, A., Hazavehei, S.M.M., Heshmati, H., Hosseini, S.H.   +5 more
core  

Recombinant LPG3 Protein From Leishmania chagasi as an Antigen for the Diagnosis of Canine Visceral Leishmaniasis

Tropical Medicine &International Health, EarlyView.
ABSTRACT Visceral leishmaniasis (VL) is a human neglected tropical disease in which dogs participate as reservoirs of the etiological agent Leishmania chagasi. The identification of infected dogs is important to the control of VL, and recombinant proteins are strong antigen candidates for canine visceral leishmaniasis (CVL) serodiagnosis. In this work,
Thaís Viana Fialho Martins, Anna Cláudia Alves de Souza, Bianca Meireles Miranda, Ronny Francisco de Souza, Daniel Silva Sena Bastos, Neverton José Silva Ferreira, Tiago Antônio de Oliveira Mendes, Celeste da Silva Freitas de Souza, George Luiz Lins Machado‐Coelho, Maria Terezinha Bahia, Leandro Licursi de Oliveira, Juliana Lopes Rangel Fietto, Eduardo de Almeida Marques‐da‐Silva   +12 more
wiley   +1 more source

Study of the Effectiveness of Drugs for the Treatment of Zoonotic Cutaneous Leishmaniasis in vivo on a Laboratory Model

Антибиотики и Химиотерапия, 2020
Confirmed evidence of sufficient effectiveness of monotherapy of zoonotic cutaneous leishmaniasis with meglumine antimonate and doxycycline in combination with interferon alpha 2b human recombinant (reaferon) has been obtained.
Yu. K. Kuznetsova
doaj