Results 61 to 70 of about 16,072 (215)

Formulation of Amphotericin B in PEGylated Liposomes for Improved Treatment of Cutaneous Leishmaniasis by Parenteral and Oral Routes

Pharmaceutics, 2022
Liposomal amphotericin B (AmB) or AmBisome® is the most effective and safe therapeutic agent for visceral leishmaniasis (VL), but its clinical efficacy is limited in cutaneous leishmaniasis (CL) and HIV/VL co-infection.
Guilherme S. Ramos, Virgínia M. R. Vallejos, Gabriel S. M. Borges, Raquel M. Almeida, Izabela M. Alves, Marta M. G. Aguiar, Christian Fernandes, Pedro P. G. Guimarães, Ricardo T. Fujiwara, Philippe M. Loiseau, Lucas A. M. Ferreira, Frédéric Frézard   +11 more
doaj   +1 more source

Cutaneous non‐tuberculous mycobacterial infections: A retrospective study of 94 cases from Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 5, Page 608-617, May 2026.
Summary Background Cutaneous non‐tuberculous mycobacterial infections (NTM) remain a diagnostic and therapeutic challenge. The aim of this study was to characterize cutaneous NTM infections in Germany over a 24‐year‐period. Patients and Methods 73 patients with cutaneous NTM infections diagnosed at 17 different German University Hospitals from 2000 ...
Luisa Bopp, Nicolai Deresz, Henning Klapproth, Isabelle Suárez, Jonathan Jantsch, Mario Fabri, Esther von Stebut   +6 more
wiley   +1 more source

The Effect of Designed Home Visit Program on Promoting Cutaneous Leishmaniasis Preventive Behaviors

نشریه پرستاری ایران, 2007
Introduction & Aim: Cutaneous Leishmaniasis is the second common parasitic disease in Iran. According to several studies, insufficient knowledge of mothers about the prevention strategies related to occurrence of the disease in their children are ...
A. Hossein nejad Nayrisi, F. Alhani, M. Anoosheh, S. Faghihzadeh   +3 more
doaj  

Therapeutic Activity of a Topical Formulation Containing 8-Hydroxyquinoline for Cutaneous Leishmaniasis

Pharmaceutics, 2023
Cutaneous leishmaniasis exhibits a wide spectrum of clinical manifestations; however, only a limited number of drugs are available and include Glucantime® and amphotericin B, which induce unacceptable side effects in patients, limiting their use.
Sarah Kymberly Santos de Lima, Ítalo Novaes Cavallone, Dolores Remedios Serrano, Brayan J. Anaya, Aikaterini Lalatsa, Márcia Dalastra Laurenti, João Henrique Ghilardi Lago, Dalete Christine da Silva Souza, Gabriela Pustiglione Marinsek, Beatriz Soares Lopes, Renata de Britto Mari, Luiz Felipe Domingues Passero   +11 more
doaj   +1 more source

Seroepidemiology and molecular diversity of Leishmania donovani complex in Georgia [PDF]

, 2016
Background Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. Visceral leishmaniasis (VL), also known as kala-azar, is a potentially fatal disease endemic to large parts of Africa and Asia, and in ...
Adeishvili, Ekaterine, Babuadze, Giorgi, Carrillo, Eugenia, Chakhunashvili, Giorgi, Chanturia, Gvantsa, De Koning, Harry P., Farlow, Jason, Imnadze, Paata, Kalandadze, Irine, Karseladze, Irakli, Kekelidze, Merab, Kokaia, Nora, Markhvashvili, Ivane, Murskvaladze, Mari, Sidamonidze, Ketevan, Tsereteli, David   +15 more
core   +3 more sources

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe, Vishal Satikuvar, Tanjia M. Syeda, Monica Cal, Pascal Mäser, Marcel Kaiser, Hachemi Kadri   +6 more
wiley   +1 more source

Natural killer cells in experimental and human leishmaniasis

Frontiers in Cellular and Infection Microbiology, 2012
Infections with parasites of the genus Leishmania lead to a rapid, but transient activation of natural killer (NK) cells. In mice activation of NK cells requires a toll-like-receptor 9-dependent stimulation of dendritic cells followed by the production ...
Christian eBogdan
doaj   +1 more source

Tongue Sarcoidosis: A Rare Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This study presents a case report with a literature review describing a rare manifestation of oral sarcoidosis involving the tongue in a 57‐year‐old woman with a prior diagnosis of cutaneous sarcoidosis. The lesion appeared as painless grayish‐white papules on the tip and dorsal surface of the tongue.
Saede Atarbashi‐Moghadam, Leyla Roghanizadeh, Ali Lotfi, Mehrab Aghdasi, Mohammadreza Kashefi Baher   +4 more
wiley   +1 more source

Enhanced Detection of Leishmania Parasites in Microscopic Images Using Machine Learning Models

Sensors
Cutaneous leishmaniasis is a parasitic disease that poses significant diagnostic challenges due to the variability of results and reliance on operator expertise.
Michael Contreras-Ramírez, Jhonathan Sora-Cardenas, Claudia Colorado-Salamanca, Clemencia Ovalle-Bracho, Daniel R. Suárez   +4 more
doaj   +1 more source

Effect of Prophylactic Vaccination with the Membrane-Bound Acid Phosphatase Gene of Leishmania mexicana in the Murine Model of Localized Cutaneous Leishmaniasis

Journal of Immunology Research, 2021
Leishmaniasis is a disease caused by an intracellular protozoan parasite of the genus Leishmania. Current treatments for leishmaniasis are long, toxic, and expensive and are not available in some endemic regions.
María Angélica Burgos-Reyes, Lidia Baylón-Pacheco, Patricia Espíritu-Gordillo, Silvia Galindo-Gómez, Víctor Tsutsumi, José Luis Rosales-Encina   +5 more
doaj   +1 more source