Results 61 to 70 of about 7,418 (172)

Nota sobre infecção natural de Oryzomys capito laticeps em foco enzoótico de leishmaniose tegumentar no Estado de São Paulo, Brasil Natural infection of Oryzomys capito laticeps in enzootic focus of cutaneous leishmaniasis in S. Paulo State, Brazil

Revista de Saúde Pública, 1973
Assinala-se o isolamento de cepa de Leishmania braziliensis braziliensis em exemplar de Oryzomys capito laticeps capturado em foco enzoótico do Estado de São Paulo, Brasil.
Oswaldo Paulo Forattini, Dino B. G. Pattoli, Ernesto Xavier Rabello, Octávio Alves Ferreira   +3 more
doaj   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Rapid and Successful Treatment of Interstitial Granulomatous Dermatitis With Tofacitinib: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Interstitial Granulomatous Dermatitis (IGD) is a rare skin condition characterized by granulomatous inflammation. Despite various treatment options, the rarity of this condition makes management challenging. This report highlights the potential of Janus kinase inhibitors, specifically Tofacitinib, as an effective therapy for IGD.
Aida Farmani, Mina Saber
wiley   +1 more source

Structural basis of ligand selectivity in FAD/NAD(P)H‐dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase

Protein Science, Volume 35, Issue 7, July 2026.
Abstract FAD/NAD(P)H‐dependent dehydrogenases form a structurally conserved family of redox enzymes that participate in essential metabolic processes across parasites and higher organisms. Among them, trypanothione reductase (TR) is a key component of the redox metabolism of Leishmania species and represents an attractive target for antileishmanial ...
Giulia Chiara Maria Perrone, Serena Spadone, Anna Lucia Francavilla, Sara Morselli, Sabino Todisco, Margherita Ortalli, Jairo Alfonso Mendoza‐Roldan, Valeria Scaglione, Maria Noemi Sgobba, Lorenzo Guerra, Federica Belluti, Stefania Varani, Domenico Otranto, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri   +15 more
wiley   +1 more source

Infecção natural de flebotomíneos em foco enzoótico de leishmaniose tegumentar no Estado de São Paulo, Brasil Natural infections of Phlebotominae sandflies in a enzootia focus of cutaneous leishmaniasis in S. Paulo State, Brasil

Revista de Saúde Pública, 1972
Relata-se o encontro de infecções naturais de Pintomyia pessoai e Psychodopygus intermedius em foco enzoótico de leishmaniose tegumentar no Estado de São Paulo, Brasil.
Oswaldo Paulo Forattini, Dino B. G. Pattoli, Ernesto Xavier Rabello, Octavio Alves Ferreira   +3 more
doaj   +1 more source

Ruminants Epidemiology, Spatial Clustering and Multivariate Risk Modelling of Cutaneous Leishmaniasis in District Bajaur, Pakistan

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This study investigated the epidemiology, risk factors and spatial distribution of cutaneous leishmaniasis in District Bajaur, Pakistan. Higher prevalence was observed among young males during summer, with lesions mainly on exposed body parts. Spatial analysis identified Khar, Loe Mamund and Salarzai as hotspots, highlighting the need for targeted ...
Murad Ali Khan, Jawad Ali, Zohaib Ali, Abdur Rehman, Muhammad Shoib, Sadaf Fayaz, Rifat Ullah Khan, Shabana Naz, Naseer Khan Momand, Antonella Perillo, Ibrahim A. Alhidary   +10 more
wiley   +1 more source

In Vitro Antiparasitic Effects of Silver Nanoparticles on Sarcocystis Bradyzoites

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
In vitro, silver nanoparticles (AgNPs) exhibit dose and time‐dependent antiparasitic activity against Sarcocystis bradyzoites from sheep, achieving up to 59.53% mortality at 800 µg/mL after 120 min. These results suggest AgNPs may be a potential alternative to traditional drugs, meriting further in vivo investigation for veterinary use.
Nasrin Karimi, Mir‐Hassan Moosavy, Nasser Hajipour, Hamed Behniafar   +3 more
wiley   +1 more source

The treatment of experimental cutaneous leishmaniasis with liposome-entrapped Pentostam

Parasitology, 1981
SUMMARYTreatment of cutaneous leishmaniasis by antimonial compounds when administered by various routes to mice infected with Leishmania major or L. mexicana amazonensis is enhanced, relative to the free drug, by entrapment of these compounds within liposomes.
R. R. C. New, M. L. Chance, S. Heath
openaire   +1 more source

Comparison of Efficacy of Intralesional Metronidazole Versus Intralesional Meglumine Antimoniate in Patients of Cutaneous Leishmaniasis

Pakistan Armed Forces Medical Journal
Objective: To compare the effectiveness of intralesional Metronidazole versus intralesional Meglumine antimoniate  in the treatment of cutaneous leishmaniasis. Study Design: Quasi experimental study.
Raisa Khan Gul, Sameena Kausar, Tehseen Naveed, Sumyra Saleem, Sarah Riaz, Ghazala Said   +5 more
doaj   +1 more source

In Vitro Effect of Methanolic Extract of Quercus infectoria Galls on Promastigotes and Amastigotes of Leishmania major (MRHO/IR/75/ER)

Medical Laboratory Journal, 2018
Background and objectives: Leishmania major is a flagellated parasitic protozoan that causes cutaneous leishmaniasis. Pentavalent antimony compounds are considered the first-line drugs in the treatment of cutaneous leishmaniasis.
Asghar Farghi Yamchi, Mansour Dabirzadeh, Yahya Maroufi   +2 more
doaj