Results 111 to 120 of about 2,979,229 (315)

Experimental Design for Matching

open access: yesCoRR
Matching mechanisms play a central role in operations management across diverse fields including education, healthcare, and online platforms. However, experimentally comparing a new matching algorithm against a status quo presents some fundamental challenges due to matching interference, where assigning a unit in one matching may preclude its ...
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Adaptive Experimental Design Using the Propensity Score [PDF]

open access: yes
Many social experiments are run in multiple waves, or are replications of earlier social experiments. In principle, the sampling design can be modified in later stages or replications to allow for more efficient estimation of causal effects.
Keisuke Hirano   +2 more
core   +2 more sources

NEW SILK: Studying Experimental Touchpoints between Material Science, Synthetic Biology, Design and Art

open access: yes, 2018
This article presents a study in which new materials are developed through experimental knowledge construction and knowledge exchange between different disciplines. The New Silk research project (2017- 2020) is the building block for the research.
Groth, Camilla   +2 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

A demonstration of the utility of fractional experimental design for finding optimal genetic algorithm parameter settings

open access: yes, 2004
This paper demonstrates that the use of sparse experimental design in the development of the structure for genetic algorithms, and hence other computer programs, is a particularly effective and efficient strategy.
Whitfield, R.I.   +3 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Navigating the Future through Experimental Policy Design

open access: yes
Innovative strategies in public policy design are crucial to effectively address the complex and interconnected environmental challenges governments face today. The intricate and uncertain nature of these problems often requires experimental coproduction
González Lago, Mariana   +1 more
core  

Contract design and insurance fraud: An experimental investigation [PDF]

open access: yes
This paper investigates the impact of insurance contract design on the behavior of filing fraudulent claims in an experimental setup. We test how fraud behavior varies for insurance contracts with full coverage, a straight deductible or variable premiums
Schiller, Jörg, Lammers, Frauke
core  

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