Results 81 to 90 of about 23,725,775 (352)
Social context prevents heat hormetic effects against mutagens during fish development
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere+5 more
wiley +1 more source
A statistical simulator scDesign for rational scRNA-seq experimental design
Motivation Single-cell RNA-sequencing (scRNA-seq) has revolutionized biological sciences by revealing genome-wide gene expression levels within individual cells.
W. Li, J. Li
semanticscholar +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
In this chapter, some of the most commonly used designs (e.g. Full Factorial, Plackett–Burman, Central Composite, Doehlert, D-Optimal, qualitative variables at more than two levels, mixture) will be presented. It will be shown how it is often possible to obtain them by hand, without using any software.
Foged, Isak Worre, Andersson, Lasse
openaire +5 more sources
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Experimental design for research on shock-turbulence interaction [PDF]
Report investigates the production of acoustic waves in the interaction of a supersonic shock and a turbulence environment. The five stages of the investigation are apparatus design, development of instrumentation, preliminary experiment, turbulence ...
Radcliffe, S. W.
core +1 more source
PLOT SIZE IN THE EVALUATION OF PAPAYA SEEDLINGS 'BAIXINHO DE SANTA AMÁLIA' IN TUBES
Were evaluated three characters in papaya seedlings 'Baixinho de Santa Amália' to estimate the optimum plot size and the number of replications in a completely randomized experiment, a randomized block and Latin square.
HUMBERTO FELIPE CELANTI+4 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
A tutorial on Quasi-experimental designs
A main step in answering a scientific hypothesis in an epidemiological study is deciding which type of study is suitable to be undertaken, considering methodology, practical considerations and budget and time ...
Reyhane sefidkar, Farzan Madadizadeh
doaj
Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution
In experimental evolution, laboratory-controlled conditions select for the adaptation of species, which can be monitored in real time. Despite the current popularity of such experiments, nature's most pervasive biological force was long believed to be ...
B. Van den Bergh+3 more
semanticscholar +1 more source