Results 81 to 90 of about 23,725,775 (352)

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

A statistical simulator scDesign for rational scRNA-seq experimental design

open access: yesbioRxiv, 2018
Motivation Single-cell RNA-sequencing (scRNA-seq) has revolutionized biological sciences by revealing genome-wide gene expression levels within individual cells.
W. Li, J. Li
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Experimental Design

open access: yes, 2013
In this chapter, some of the most commonly used designs (e.g. Full Factorial, Plackett–Burman, Central Composite, Doehlert, D-Optimal, qualitative variables at more than two levels, mixture) will be presented. It will be shown how it is often possible to obtain them by hand, without using any software.
Foged, Isak Worre, Andersson, Lasse
openaire   +5 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Experimental design for research on shock-turbulence interaction [PDF]

open access: yes, 1969
Report investigates the production of acoustic waves in the interaction of a supersonic shock and a turbulence environment. The five stages of the investigation are apparatus design, development of instrumentation, preliminary experiment, turbulence ...
Radcliffe, S. W.
core   +1 more source

PLOT SIZE IN THE EVALUATION OF PAPAYA SEEDLINGS 'BAIXINHO DE SANTA AMÁLIA' IN TUBES

open access: yesRevista Brasileira de Fruticultura
Were evaluated three characters in papaya seedlings 'Baixinho de Santa Amália' to estimate the optimum plot size and the number of replications in a completely randomized experiment, a randomized block and Latin square.
HUMBERTO FELIPE CELANTI   +4 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

A tutorial on Quasi-experimental designs

open access: yesJournal of Community Health Research, 2022
A main step in answering a scientific hypothesis in an epidemiological study is deciding which type of study is suitable to be undertaken, considering methodology, practical considerations and budget and time ...
Reyhane sefidkar, Farzan Madadizadeh
doaj  

Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution

open access: yesMicrobiology and Molecular Biology Reviews, 2018
In experimental evolution, laboratory-controlled conditions select for the adaptation of species, which can be monitored in real time. Despite the current popularity of such experiments, nature's most pervasive biological force was long believed to be ...
B. Van den Bergh   +3 more
semanticscholar   +1 more source

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