Results 61 to 70 of about 1,227,115 (260)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Examining charter school policy and public school district resource allocation in Ohio
Education Policy Analysis Archives, 2016 This project focuses on the competitive pressure, or the threat of competitive pressure, generated by charter school policy. This paper uses longitudinal district-level data and multiple quasi-experimental designs to examine the relationship between two ...
Matthew Allen Linick
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
New Computer Experiment Designs with Area-Interaction Point Processes
MathematicsThis article presents a novel method for constructing computer experiment designs based on the theory of area-interaction point processes. This method is essential for capturing the interactions between different elements within a modeled system ...
Ahmed Ait Ameur +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
European Journal of General PracticeBackground Rapid identification of effective treatments for use in the community during a pandemic is vital for the well-being of individuals and the sustainability of healthcare systems and society.
Christopher C. Butler
doaj +1 more source
Fish Attraction Devices (FADs) and experimental designs
Scientia Marina, 1999 There is widespread use of fish attraction devices (FADs) in commercial fisheries and research. Investigations on the utility of FADs to catch fishes, and factors influencing fishes associated with FADs, require careful consideration of experimental ...
Michael J. Kingsford
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Neural Network Assisted Experimental Designs for Food Research
Journal of Agricultural and Marine Sciences, 2000 The ability of artificial neural networks (ANN) in predicting full factorial data from the fractional data corresponding to some of the commonly used experimental designs is explored in this paper.
H.S. Ramaswamy +4 more
doaj +3 more sources
Clinical research study designs: The essentials
Pediatric Investigation, 2019 In clinical research, our aim is to design a study which would be able to derive a valid and meaningful scientific conclusion using appropriate statistical methods. The conclusions derived from a research study can either improve health care or result in
Ambika G. Chidambaram, Maureen Josephson
doaj +1 more source