Results 111 to 120 of about 934,796 (284)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Effect of external operational damage on the mechanical behavior of GFRP under quasi-static and fatigue loading

Fracture and Structural Integrity
An experimental study was conducted to investigate the influence of operational defects, such as surface scratches and dents, on the residual mechanical properties of glass fiber-reinforced plastic (GFRP) during quasi-static tensile and fatigue tests ...
Anastasia Lykova, D.S. Lobanov, A.M. Pankov   +2 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Numerical study of the influence of the parameters of statistical distribution of the structural elements’ ultimate strength on deformable bodies’ fracture processes

Fracture and Structural Integrity
This work is dedicated to the numerical study of the influence of the parameters of statistical distribution of the structural elements’ ultimate strength on fracture processes of deformable bodies with stress concentrators.
Eugeniia Feklistova, Artur Mugatarov, Valeriy Wildemann   +2 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

An Evolutionary Formalism for Weak Quantum Measurements

, 2015
Unitary evolution and projective measurement are fundamental axioms of quantum mechanics. Even though projective measurement yields one of the eigenstates of the measured operator as the outcome, there is no theory that predicts which eigenstate will be ...
Kumar, Parveen, Patel, Apoorva
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Experimental Fluid Mechanics 2018 [PDF]

EPJ Web of Conferences, 2019
Dančová Petra
doaj   +1 more source

Structural–kinematic synthesis of a long-dwell, allowable transmission angle two-rod mechanism for a knuckle joint press

Cogent Engineering
The main advantage of the proposed knuckle joint press mechanism over traditional crank presses is the extended dwell time, which enables better control over the stamping process.
Amandyk Tuleshov, Assylbek Jomartov, Moldir Kuatova, Recep Halicioglu   +3 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source