Results 111 to 120 of about 349,012 (301)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Theoretical modal analysis of freely and simply supported RC slabs [PDF]
, 2014 This paper focuses on the dynamic behavior of reinforced concrete (RC) slabs. Therefore, the theoretical modal analysis was performed using two different types of boundary conditions. Modal analysis method is the most important dynamic analyses.
Ahmed, MS, Mohammad, FA
core
, 2019 In this work, we introduce a novel algorithm for solving the textbook question answering (TQA) task which describes more realistic QA problems compared to other recent tasks. We mainly focus on two related issues with analysis of the TQA dataset.
Kim, Daesik, Kim, Seonhoon, Kwak, Nojun
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Structural Modal Time Domain Identification Method Based on the Bayesian Uncertain Quantification
Applied SciencesBased on the Bayesian framework, a time domain method is proposed for the uncertain quantification of structural modal identification. First, a theoretical prediction model is constructed from the state space model in modal space and then transformed ...
Yaozong Pan, Yan Zhao
doaj +1 more source
Dynamic characteristics of a vibrating beam with periodic variation in bending stiffness [PDF]
A detailed dynamic analysis is performed of a vibrating beam with bending stiffness periodic in the spatial coordinate. The effects of system parameters on beam response are explored with a perturbation expansion technique.
Townsend, John S.
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Experimental Modal Analysis of Scaled Car-body Sidewall for High-speed Vehicles
机车电传动, 2017 According to the theory of experimental modal analysis (EMA), SIMO analysis method, multi-reference point modal test, experimental modal test and modal parameters identification of the scaled 1:8 car-body’s sidewall were conducted.
LI Xujuan +4 more
doaj
Bayesian FFT modal identification for multi-setup experimental modal analysis
Mechanical Systems and Signal ProcessingIn full-scale forced vibration tests, the demand often arises to capture high-spatial-resolution mode shapes with limited number of sensors and shakers. Multi-setup experimental modal analysis (EMA) addresses this challenge by roving sensors and shakers across multiple setups.
Peixiang Wang, Binbin Li
openaire +2 more sources
And yet another method for the identification of modal constants in experimental modal analysis [PDF]
, 2017 Modal Identification from Frequency Response Functions (FRFs) is a chapter of Experimental Modal Analysis (EMA) that many would consider being closed in a book and covered in dust.
Amafabia, D.M. +2 more
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