Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Identification of the modal masses of an UAV structure in operational environment
In the framework of Operational Modal Analysis, several methods have been developed to estimate the modal parameters, that is natural frequencies, damping ratios, and mode shapes of a structure in its operative conditions.
Arras, M. +2 more
core
Methods for modal parameters identification applied to CNC machine tool feed drives [PDF]
The paper presents a critical appraisal of existing methods for the identification of modal parameters (natural frequencies, damping ratios and mode shapes) for CNC machine tool feed drives.
Widiyarto, Muhammad Helmi Nur +3 more
core +4 more sources
Spatially Resolved Experimental Modal Analysis on High-Speed Composite Rotors Using a Non-Contact, Non-Rotating Sensor. [PDF]
Lich J +5 more
europepmc +1 more source
Bayesian FFT modal identification for multi-setup experimental modal analysis
In full-scale forced vibration tests, the demand often arises to capture high-spatial-resolution mode shapes with limited number of sensors and shakers. Multi-setup experimental modal analysis (EMA) addresses this challenge by roving sensors and shakers across multiple setups.
Peixiang Wang, Binbin Li
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Modal Parameter Estimation of a PVC-product Cleaning Machine by means of Operational Modal Analysis [PDF]
The prototype of a machine tool for the fine machining of PVC window casings was recently developed and tested. Preliminary tests pointed out that excessive vibrations arise during the execution of some operative motion laws, possibly affecting the ...
TRONCOSSI, MARCO, RIVOLA, ALESSANDRO
core +1 more source
In order to improve the dynamic performance of the grinding machine and improve the machining precision of the machine tool, a modal experiment is conducted on the complete machine and main sub-structures of the series-parallel hybrid grinding and ...
Qu Xing-tian, Zhang Jia-he, Wang Xin
doaj +1 more source
Modal Test Reference Selection for Experimental Modal Analysis.
The conventional method for modal test reference selection based on singular value decomposition of measured frequency response function matrices needs large numbers of selection processes, when many reference locations are initially proposed or many modes exist in the analysis frequency range. An alternative procedure to identify the least numbers and
openaire +2 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source

