Results 141 to 150 of about 8,545,961 (198)
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Experimental Models of Dystonia

2011
Dystonia is a disabling movement disorder characterized by involuntary, sustained muscle contractions, with repetitive twisting movements and abnormal postures. It is clinically classified as primary, either sporadic or genetic, or secondary, following focal brain lesions. The recent past has witnessed remarkable progress in finding genes for dystonia.
Tassone, A   +4 more
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Experimental bilayer membrane models

Protoplasma, 1967
The structure of cellular membranes is a central problem in biology. Interest in structure at the subcellular level derives primarily from the realization that the functional properties of biological membranes are a product of the molecular arrangement and the physical properties of the component molecules.
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Cytogenetics and experimental models

Current Opinion in Oncology, 1997
The use of cytogenetics has led to significant improvement in the diagnoses and classification of sarcomas. Many of the major sarcomas have been to have characteristic tumor-specific chromosomal translocations that are currently used in the diagnosis of these tumors.
J A, Toretsky, L J, Helman
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Experimental Models of Schizophrenia

International Journal of Neuroscience, 1991
The Kraepelinian subtypes, developed early in the century, recognize the heterogeneity of schizophrenia but do not reliably predict differences in response to classical neuroleptics. The newer distinction of positive and negative syndromes in schizophrenia carry promise as an approach to identifying meaningful clinical and neurobiological dimensions ...
S R, Kay, R, Sandyk
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Experimental models in rhinitis

Clinical & Experimental Allergy, 1999
Nasal challenge with allergen or mediators is a useful model to understand the pathophysiology of allergic rhinitis. Some mechanisms have thereby been clearly clarified. Different methods have been proposed to mimic the natural allergen exposure and to measure the clinical and biological responses. Nasal challenges can also be used in clinical practice,
P, Demoly   +3 more
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Experimental Model for Scleritis

Archives of Ophthalmology, 1979
Rabbits were sensitized over a prolonged period to ovalbumin by intradermal injection. Ovalbumin was then injected into the limbus of the eye. A corneoscleral lesion, similar to necrotizing scleritis in humans, was produced. The clinical progression of the lesion is described and its histologic appearance discussed in relation to the human disease.
R M, Hembry   +3 more
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Experimental Model of Varicocele

European Urology, 1989
The purpose of this investigation was to create a varicocele model in animals and to study the subsequent alterations in testicular physiology. The study comprised 22 dogs divided into 2 groups: test and control. In the test group (17 dogs), excision of a longitudinal strip of the fasciomuscular tube of the spermatic cord was done on one side only.
A, Shafik   +6 more
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Cachexia in experimental models

Nutrition, 1999
Cachexia refers to a state of severe malnutrition characterized by anorexia, weight loss, and muscle wasting. Although it is most commonly considered in the context of cancer, it may occur as a consequence of a variety of chronic diseases. Cachexia appears to differ from "semistarvation" in that there is evidence of metabolic changes that are different
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Experimental models of asthma

Lung, 1982
Ideally, animal models of bronchial asthma should exhibit most if not all features of human bronchial asthma. The general aim of developing such animal models has undoubtedly been to reproduce the human disease in order to study its pathophysiology and pathogenesis.
A, Wanner, W M, Abraham
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