Results 121 to 130 of about 3,119,335 (269)

A theoretical and experimental model of flow characteristics in subretinal injections. [PDF]

PLoS One
Ladha R, Merveille B, Wyns R, Scheid B, Willermain F, de Smet MD.   +5 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Recurrent intermittent hyponatremia: A new experimental model. [PDF]

PLoS One
Tejedor M, Cussó L, González-Nicolás MÁ, San Felipe D, Calle D, Martín-Sánchez B, Uzun B, Martín-Palumbo G, Alvarez-Sala Walther LA, Marco EM, López-Gallardo M, Lázaro A, Desco M.   +12 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Empagliflozin and renal histological changes in an experimental model of heart failure in male rats. [PDF]

Physiol Rep
Wisnivesky ACT, Bertacchi JGF, Caramelli B.   +2 more
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Adverse Cardiometabolic Impacts of Sleep Fragmentation and Estradiol Suppression: An Experimental Model of Menopause. [PDF]

J Clin Endocrinol Metab
Rahman SA, Grant LK, Cohn AY, Harder JA, Nathan MD, Gonsalvez I, Wiley A, Mora S, Taylor JA, Scheer FAJL, Klerman EB, Kaiser UB, Crawford S, Joffe H.   +13 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Assessment of the efficiency of new regenerative gel and spray in experimental model systems. [PDF]

BMC Pharmacol Toxicol
Bezdieniezhnykh N, Lykhova O, Borshchevska M, Goy A, Saulenko K, Kozak T, Kukurudza D, Kruglov Y, Borshchevskiy G, Buchynska L.   +9 more
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source