Results 61 to 70 of about 8,545,961 (198)

Engraftment of human mesenchymal stem cells in a severely immunodeficient mouse

Inflammation and Regeneration
The transplantation of human mesenchymal stromal/stem cells (hMSCs) has potential as a curative and permanent therapy for congenital skeletal diseases. However, the self-renewal and differentiation capacities of hMSCs markedly vary.
Yuko Kato, Yusuke Ohno, Ryoji Ito, Takeshi Taketani, Yumi Matsuzaki, Satoru Miyagi   +5 more
doaj   +1 more source

Integrative Analysis of Omics Data in Animal Models of Coronavirus Infection

Shiyan dongwu yu bijiao yixue
ObjectiveThis study analyzes the omics data resources in human-infecting coronavirus animal models collected from various public databases, focusing on data distribution, dataset quantity, data types, species, strains, and research content.
WU Yue, LI Lu, ZHANG Yang, WANG Jue, FENG Tingting, LI Yitong, WANG Kai, KONG Qi   +7 more
doaj   +1 more source

Experimental Characterization of the Ising Model in Disordered Antiferromagnets

, 2000
The current status of experiments on the d=2 and d=3 random-exchange and random-field Ising models, as realized in dilute anisotropic antiferromagnets, is discussed. Two areas of current investigation are emphasized. For d=3, the large random field limit
Belanger, D. P.
core   +2 more sources

Experimental models in epilepsy

Neurología (English Edition), 2010
epilepsy is one of the neurological pathologies with the highest rate of incidence and with a significant number of negatives consequences. Current pharmacological treatments have an antiepileptic effect, allowing control over 70% of the patients, but they are not able to prevent the development of epileptogenesis from occurring.ee have reviewed the ...
M.E. Garcia Garcia, I. Garcia Morales, J. Matías Guiu   +2 more
openaire   +3 more sources

Intestinal Gastrin/CCKBR Axis Protects against Type 2 Diabetes by Reducing Intestinal Glucose Absorption through the PI3K/Akt/eIF4B Signaling Pathway

Advanced Science
The Gastrin/CCKBR axis is essential for inhibiting intestinal sodium absorption, but its effects on intestinal glucose metabolism remain elusive. This study aims to determine the role of intestinal Gastrin/CCKBR on glucose absorption in the development ...
Xue Liu, Xing Liu, Yunpeng Liu, Anxiong Long, Wei Liu, Shiyun Sun, Shuaibing Lu, Xianxian Wu, Xiaodi Jia, Pedro A Jose, Qiang Wei, Xiaoliang Jiang, Haizeng Zhang, Zhiwei Yang   +13 more
doaj   +1 more source

Exposure to diverse airborne bacterial communities following Klebsiella pneumoniae infection elicits distinct host response mechanisms in mice

Ecotoxicology and Environmental Safety
Background: Air harbors diverse microorganisms. However, the influence of airborne microbial communities on the recovery phase of pneumonia patients remains inadequately explored.
Chenchen Song, Li Zhou, Lianlian Zhao, Zhi Guo, Lifang Zhang, Hu Yang, Yuhan Lei, Yunlin Han, Yanfeng Xu, Zhiguang Xiang, Baicun Li, Jianguo Guo   +11 more
doaj   +1 more source

Experimental Status of Beyond the Standard Model Collider Searches

, 2005
This is a brief review of experimental strategies for physics beyond the Standard Model based on the talk given in the ``Physics at LHC'' in Vienna, July 2004 \cite{vienna}. The emphasis is on Tevatron thematology and experience.Comment: "Physics at LHC"
Spiropulu, M.
core  

Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]

, 2009
This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Bates, D.G., Heslop-Harrison, P., Kim, J.-R., Kim, J.-S., Postlethwaite, I.   +4 more
core  

Sensitivity dependent model of protein-protein interaction networks

, 2008
The scale free structure p(k)~k^{-gamma} of protein-protein interaction networks can be reproduced by a static physical model in simulation. We inspect the model theoretically, and find the key reason for the model to generate apparent scale free degree ...
Estojak J, Eugene I Shakhnovich, Jingshan Zhang, Wagner A   +3 more
core   +1 more source

Development of a DNA damage assay system using stable human hepatocytes

Genes and Environment
Background Overcoming species differences in metabolism between humans and animals remains a critical challenge in toxicological studies. Rat liver S9 fraction has long been the gold standard for exogenous metabolic activation in in vitro genotoxicity ...
Masayuki Mishima, Kazuki Izawa, Masataka Tsuda, Yuichiro Higuchi, Shotaro Uehara, Hiroshi Suemizu, Kei-Ichi Sugiyama   +6 more
doaj   +1 more source