Results 41 to 50 of about 8,617,954 (300)

Automated Assessment of Endpoint and Kinematic Features of Skilled Reaching in Rats

Frontiers in Behavioral Neuroscience, 2018
Background: Neural injury to the motor cortex may result in long-term impairments. As a model for human impairments, rodents are often used to study deficits related to reaching and grasping, using the single-pellet reach-to-grasp task.
Ioana Nica, Marjolijn Deprez, Bart Nuttin, Bart Nuttin, Jean-Marie Aerts   +4 more
doaj   +1 more source

Cfdp1 Is Essential for Cardiac Development and Function

Cells, 2023
Cardiovascular diseases (CVDs) are the prevalent cause of mortality worldwide. A combination of environmental and genetic effectors modulates the risk of developing them.
Panagiota Giardoglou, Panos Deloukas, George Dedoussis, Dimitris Beis   +3 more
doaj   +1 more source

Internally Electrodynamic Particle Model: Its Experimental Basis and Its Predictions

, 2010
The internally electrodynamic (IED) particle model was derived based on overall experimental observations, with the IED process itself being built directly on three experimental facts, a) electric charges present with all material particles, b) an ...
A. H. Bucherer, A. Tonomura, B. Brezger, C. D. Anderson, C. Davisson, Ch. E. Guye, D. Griffiths, D. P. Mitchell, E. Schrödinger, F. Joliot, F. R. Elder, G. P. Thomson, G. T. Gillies, H. Halban, H.-D. Doebner, I. Estermann, J. Stark, J. Thibaud, J. W. M. DuMond, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, J. X. Zheng-Johansson, L. Broglie de, M. Planck, O. Klemperer, P. A. M. Dirac, P. G. Merli, P. M. S. Blackett, W. Kaufmann, W. M. Elsasser, Y. Yoshizawa   +35 more
core   +1 more source

The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer [PDF]

, 2009
More than 60% of all breast neoplasias are ductal carcinomas expressing estrogen (ER) and progesterone receptors (PR). In contrast, most of the spontaneous, chemically or MMTV induced tumors, as well as tumors arising in genetically modified mice do not ...
Bottino, Maria Cecilia, Cerliani, Juan Pablo, Fabris, Victoria Teresa, Giulianelli, Sebastian Jesus, Helguero, Luisa A., Lamb, Caroline Ana, Lanari, Claudia Lee Malvina, Molinolo, Alfredo, Soldati, Rocío, Wargon, Victoria   +9 more
core   +1 more source

Experimental models of epilepsy

Medicinski pregled, 2004
Introduction An epileptic seizure is a clinical event and epilepsy is rather a group of symptoms than a disease. The main features all epilepsies have in common include: spontaneous occurrence, repetitiveness, and ictal correlation within the EEG. Epilepsies are manifested with distinct EEG changes, requiring exact clinical definition and consequential
Olivera P, Stanojlović, Dragana P, Zivanović   +1 more
openaire   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Advances in Innate Immunity to Overcome Immune Rejection during Xenotransplantation

Cells, 2022
Transplantation is an effective approach for treating end-stage organ failure. There has been a long-standing interest in xenotransplantation as a means of increasing the number of available organs.
Tian-Yu Lu, Xue-Ling Xu, Xu-Guang Du, Jin-Hua Wei, Jia-Nan Yu, Shou-Long Deng, Chuan Qin   +6 more
doaj   +1 more source

Experimental models of stress

Dialogues in Clinical Neuroscience, 2006
Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on naturalistic stressors, pharmacological challenges, and genomic manipulations is complemented by ...
Vladimir K, Patchev, Alexandre V, Patchev   +1 more
openaire   +3 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source