Results 31 to 40 of about 8,617,954 (300)

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Investigation the mechanism of iron overload-induced colonic inflammation following ferric citrate exposure

Ecotoxicology and Environmental Safety
Iron overload occurs due to excessive iron intake compared to the body’s demand, leading to iron deposition and impairment of multiple organ functions. Our previous study demonstrated that chronic oral administration of ferric citrate (FC) caused colonic
Yu Xia, Zhengli Chen, Chao Huang, Liangqin Shi, Wenjing Ma, Xiwen Chen, Yucong Liu, Yao Wang, Chunyu Cai, Yixiang Huang, Wentao Liu, Riyi Shi, Qihui Luo   +12 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells

Frontiers in Immunology, 2017
Type I (α and β) and type III (λ) interferons (IFNs) induce the expression of a large set of antiviral effector molecules via their respective surface membrane receptors.
Tharini A. Selvakumar, Tharini A. Selvakumar, Sudeep Bhushal, Ulrich Kalinke, Dagmar Wirth, Dagmar Wirth, Hansjörg Hauser, Mario Köster, Mathias W. Hornef   +8 more
doaj   +1 more source

Experimental Models of Cryptococcosis [PDF]

International Journal of Microbiology, 2012
Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction.
Wilber Sabiiti, Robin C. May, E. Rhiannon Pursall   +2 more
openaire   +5 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

A combined experimental-numerical study to tensile behaviour of limestone [PDF]

, 2003
In this paper, a combined experimental-computational study of double-edge notched stone specimen subject to cyclic tensile loading is presented. In the experimental part, the load-deformation response and the local displacement field are recorded.
,, De Proft, K, De Wilde, WP, Sluys, LJ, Wells, GN   +4 more
core  

Possible Experimental Test of Continuous Medium Model for Fractal Media

, 2005
We use the fractional integrals to describe fractal media. We consider the fractal media as special ("fractional") continuous media. We discuss the possible experimental testing of the continuous medium model for fractal media that is suggested in Phys ...
Avnir, Bale, Beran, Christensen, Collins, Katz, Le Mehaute, Mandelbrot, Pfeifer, Ren, Samko, Samko, Schaefer, Schaefer, Schroeder, Tarasov, Tarasov, Tarasov, Tarasov, Tarasov, Vasily E. Tarasov, Zaslavsky, Zaslavsky   +22 more
core   +2 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study

Journal of Ophthalmology, 2019
Purpose. To investigate the changes of thickness in each layer, the morphology and density of inner neurons in rhesus monkeys’ retina at various growth stages, thus contribute useful data for further biological studies. Methods.
Jingfei Chen, Qihui Luo, Chao Huang, Wen Zeng, Ping Chen, Qi Gao, Bing Chen, Wentao Liu, Lingzhen Pan, Zhengli Chen   +9 more
doaj   +1 more source