Results 31 to 40 of about 3,110,162 (269)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Investigation the mechanism of iron overload-induced colonic inflammation following ferric citrate exposure

Ecotoxicology and Environmental Safety
Iron overload occurs due to excessive iron intake compared to the body’s demand, leading to iron deposition and impairment of multiple organ functions. Our previous study demonstrated that chronic oral administration of ferric citrate (FC) caused colonic
Yu Xia, Zhengli Chen, Chao Huang, Liangqin Shi, Wenjing Ma, Xiwen Chen, Yucong Liu, Yao Wang, Chunyu Cai, Yixiang Huang, Wentao Liu, Riyi Shi, Qihui Luo   +12 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells

Frontiers in Immunology, 2017
Type I (α and β) and type III (λ) interferons (IFNs) induce the expression of a large set of antiviral effector molecules via their respective surface membrane receptors.
Tharini A. Selvakumar, Tharini A. Selvakumar, Sudeep Bhushal, Ulrich Kalinke, Dagmar Wirth, Dagmar Wirth, Hansjörg Hauser, Mario Köster, Mathias W. Hornef   +8 more
doaj   +1 more source

Experimental Models of Brugada syndrome [PDF]

International Journal of Molecular Sciences, 2019
Brugada syndrome is an inherited, rare cardiac arrhythmogenic disease, associated with sudden cardiac death. It accounts for up to 20% of sudden deaths in patients without structural cardiac abnormalities. The majority of mutations involve the cardiac sodium channel gene SCN5A and give rise to classical abnormal electrocardiogram with ST segment ...
Franziska Sendfeld, Elisabet Selga, Fabiana S. Scornik, Guillermo J. Pérez, Nicholas L. Mills, Ramon Brugada   +5 more
openaire   +4 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Experimental models of stress

Dialogues in Clinical Neuroscience, 2006
Illustrating the complexity of the stress response and its multifaceted manifestations is the leading idea of this overview of experimental paradigms used for stress induction in laboratory animals. The description of key features of models based on naturalistic stressors, pharmacological challenges, and genomic manipulations is complemented by ...
Vladimir K, Patchev, Alexandre V, Patchev   +1 more
openaire   +3 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study

Journal of Ophthalmology, 2019
Purpose. To investigate the changes of thickness in each layer, the morphology and density of inner neurons in rhesus monkeys’ retina at various growth stages, thus contribute useful data for further biological studies. Methods.
Jingfei Chen, Qihui Luo, Chao Huang, Wen Zeng, Ping Chen, Qi Gao, Bing Chen, Wentao Liu, Lingzhen Pan, Zhengli Chen   +9 more
doaj   +1 more source

Automated Assessment of Endpoint and Kinematic Features of Skilled Reaching in Rats

Frontiers in Behavioral Neuroscience, 2018
Background: Neural injury to the motor cortex may result in long-term impairments. As a model for human impairments, rodents are often used to study deficits related to reaching and grasping, using the single-pellet reach-to-grasp task.
Ioana Nica, Marjolijn Deprez, Bart Nuttin, Bart Nuttin, Jean-Marie Aerts   +4 more
doaj   +1 more source