Results 11 to 20 of about 3,110,162 (269)

Experimental Models of Pancreatitis

open access: yesClinical Endoscopy, 2014
Acute pancreatitis is an inflammatory disease characterized by interstitial edema, inflammatory cell infiltration, and acinar cell necrosis, depending on its severity. Regardless of the extent of tissue injury, acute pancreatitis is a completely reversible process with evident normal tissue architecture after recovery. Its pathogenic mechanism has been
Hyun, Jong Jin, Lee, Hong Sik
openaire   +2 more sources

Screening for urinary markers predicting hematopoietic stem cell injury induced by busulfan using genetically diverse mice

open access: yesAnimal Models and Experimental Medicine, 2023
Background Busulfan (BU) is an alkylating agent used as a conditioning agent prior to hematopoietic stem cell (HSC) transplantation as it is known to be cytotoxic to host hematopoietic stem and progenitor cells.
Yuhang Sun   +6 more
doaj   +1 more source

Low Cycle Fatigue and Relaxation Performance of Ferritic–Martensitic Grade P92 Steel

open access: yesMetals, 2019
Due to their excellent creep resistance and good oxidation resistance, 9–12% Cr ferritic–martensitic stainless steels are widely used as high temperature construction materials in power plants.
Maria Jürgens   +3 more
doaj   +1 more source

Soy Isoflavones Regulate Lipid Metabolism through an AKT/mTORC1 Pathway in Diet-Induced Obesity (DIO) Male Rats

open access: yesMolecules, 2016
The pandemic tendency of obesity and its strong association with serious co-morbidities have elicited interest in the underlying mechanisms of these pathologies.
Chao Huang   +9 more
doaj   +1 more source

Experimental models in epilepsy

open access: yesNeurología (English Edition), 2010
epilepsy is one of the neurological pathologies with the highest rate of incidence and with a significant number of negatives consequences. Current pharmacological treatments have an antiepileptic effect, allowing control over 70% of the patients, but they are not able to prevent the development of epileptogenesis from occurring.ee have reviewed the ...
M.E. Garcia Garcia   +2 more
openaire   +3 more sources

Experimental models for nephropathy [PDF]

open access: yesJournal of the Renin-Angiotensin-Aldosterone System, 2008
Nephropathy is a leading cause of morbidity and mortality and its prevalence is continuously increasing in industrialised nations. Nephropathy is characterised to varying degrees by nodular glomerulosclerosis, glomerular basement membrane thickness and mesangial expansion, leading to a decline in glomerular filtration rate, persistent elevated ...
Pitchal, Balakumar   +5 more
openaire   +2 more sources

An altered gut microbiota in duck-origin parvovirus infection on cherry valley ducklings is associated with mucosal barrier dysfunction

open access: yesPoultry Science, 2021
Duck-origin parvovirus disease is an epidemic disease mainly caused by duck-origin goose parvovirus (D-GPV), which is characterized by beak atrophy and dwarfism syndrome.
Qihui Luo   +10 more
doaj   +1 more source

Experimental models of epilepsy

open access: yesMedicinski pregled, 2004
Introduction An epileptic seizure is a clinical event and epilepsy is rather a group of symptoms than a disease. The main features all epilepsies have in common include: spontaneous occurrence, repetitiveness, and ictal correlation within the EEG. Epilepsies are manifested with distinct EEG changes, requiring exact clinical definition and consequential
Olivera P, Stanojlović   +1 more
openaire   +3 more sources

PGC-1α-Coordinated Hypothalamic Antioxidant Defense Is Linked to SP1-LanCL1 Axis during High-Fat-Diet-Induced Obesity in Male Mice

open access: yesAntioxidants
High-fat-diet (HFD)-induced obesity parallels hypothalamic inflammation and oxidative stress, but the correlations between them are not well-defined. Here, with mouse models targeting the antioxidant gene LanCL1 in the hypothalamus, we demonstrate that ...
Shuai Shi   +11 more
doaj   +1 more source

Experimental Models for Psoriasis

open access: yesJournal of Investigative Dermatology, 1990
Evidence suggests that inherent in skin of psoriatic subjects are cells, architectural structures, and/or mediators, which are, at a minimum, responsible for its hyperproliferative epidermis. An objective of our laboratory has been to establish an in vitro definition of this inherent aberration.
Krueger, G.G., Jorgensen, C.M.
openaire   +2 more sources

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