Results 21 to 30 of about 34,125,379 (266)

The short-lived African turquoise killifish: an emerging experimental model for ageing

Disease Models & Mechanisms, 2016
Human ageing is a fundamental biological process that leads to functional decay, increased risk for various diseases and, ultimately, death. Some of the basic biological mechanisms underlying human ageing are shared with other organisms; thus, animal ...
Yumi Kim, H. Nam, D. Valenzano
semanticscholar   +1 more source

SHEEP AS AN EXPERIMENTAL MODEL FOR BIOMATERIAL IMPLANT EVALUATION

Acta Ortopédica Brasileira, 2016
Objective: Based on a literature review and on our own experience, this study proposes sheep as an experimental model to evaluate the bioactive capacity of bone substitute biomaterials, dental implant systems and orthopedics devices.
S. Sartoretto, M. Uzeda, F. Miguel, Jhonathan Raphaell Nascimento, F. O. Ascoli, M. Calasans-Maia   +5 more
semanticscholar   +1 more source

An altered gut microbiota in duck-origin parvovirus infection on cherry valley ducklings is associated with mucosal barrier dysfunction

Poultry Science, 2021
Duck-origin parvovirus disease is an epidemic disease mainly caused by duck-origin goose parvovirus (D-GPV), which is characterized by beak atrophy and dwarfism syndrome.
Qihui Luo, Xinyu Lei, Jing Xu, Asad Jahangir, Junbo He, Chao Huang, Wentao Liu, Anchun Cheng, Li Tang, Yi Geng, Zhengli Chen   +10 more
doaj   +1 more source

PGC-1α-Coordinated Hypothalamic Antioxidant Defense Is Linked to SP1-LanCL1 Axis during High-Fat-Diet-Induced Obesity in Male Mice

Antioxidants
High-fat-diet (HFD)-induced obesity parallels hypothalamic inflammation and oxidative stress, but the correlations between them are not well-defined. Here, with mouse models targeting the antioxidant gene LanCL1 in the hypothalamus, we demonstrate that ...
Shuai Shi, Jichen Wang, Huan Gong, Xiaohua Huang, Bin Mu, Xiangyu Cheng, Bin Feng, Lanlan Jia, Qihui Luo, Wentao Liu, Zhengli Chen, Chao Huang   +11 more
doaj   +1 more source

Taenia solium: Development of an Experimental Model of Porcine Neurocysticercosis

PLoS Neglected Tropical Diseases, 2015
Human neurocysticercosis (NC) is caused by the establishment of Taenia solium larvae in the central nervous system. NC is a severe disease still affecting the population in developing countries of Latin America, Asia, and Africa. While great improvements
A. Fleury, A. Trejo, Humberto Cisneros, Roberto García-Navarrete, N. Villalobos, M. Hernández, J. Villeda Hernández, B. Hernández, G. Rosas, R. Bobes, Aline S. de Aluja, E. Sciutto, G. Fragoso   +12 more
semanticscholar   +1 more source

ALDH1a3 Protects Against Iron Overload−Induced Oxidative Stress and Mitochondrial Impairment in Renal Tubular Epithelial Cells

Antioxidants
Iron overload significantly contributes to chronic kidney disease progression by triggering oxidative stress and mitochondrial impairment via the Fenton reaction.
Tingting Wei, Zongliang Xiong, Tianci Wang, Chao Huang, Qihui Luo, Riyi Shi, Lanlan Jia, Wentao Liu, Donghui Yang, Zhengli Chen   +9 more
doaj   +1 more source

INVARIANT MODEL FOR ESTIMATION OF THE ATMOSPHERE TRANSMITTING EFFICIENCY AT OBJECTS MONITORING IN THE OPTICAL SPECTRAL RANGE [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2012
Estimation problem of the atmosphere influence on radiation in the middle and distant infra-red range for the increasing of results reliability at aircraft monitoring is considered.
A. V. Demin, M. Ianalytical model, identification, the atmosphere transmitting efficiency, objects monitoring, experimental data. Moiseeva   +1 more
doaj  

Autoimmunity to type II collagen an experimental model of arthritis

Journal of Experimental Medicine, 1977
We have found that intradermal injection of native type II collagen extracted from human, chick or rat cartilage induces an inflammatory arthritis in approximately 40% of rats of several strains whether complete Freund's adjuvant or incomplete Freund's ...
D. Trentham, Alexander S. Townes, A. Kang   +2 more
semanticscholar   +1 more source

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

Scientific Reports, 2016
Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells.
V. Cappello, L. Marchetti, P. Parlanti, Silvia Landi, I. Tonazzini, M. Cecchini, V. Piazza, M. Gemmi   +7 more
semanticscholar   +1 more source

Dimercaprol Reprograms Intestinal Redox Homeostasis and Organelle Crosstalk to Combat Iron-Induced Gut Dysbiosis Through NRF2/HO-1 Signaling

Antioxidants
Gut disorders are largely caused by iron-induced microbial dysbiosis. Excess iron disrupts barrier integrity by inducing oxidative stress, leading to impaired cellular processes.
Asad Khan, Zongliang Xiong, Iftikhar Ali Khan, Xiangyu Cheng, Qihui Luo, Lanlan Jia, Wentao Liu, Chao Huang, Zhengli Chen   +8 more
doaj   +1 more source