Results 61 to 70 of about 8,617,954 (300)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Heterogeneous nuclear ribonucleoprotein K promotes the progression of lung cancer by inhibiting the p53‐dependent signaling pathway

Thoracic Cancer, 2022
Background Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is a nucleic acid‐binding protein. Reportedly, hnRNPK is overexpressed in many human tumors, and such overexpression is associated with poor prognosis, implicating the role of hnRNPK as an ...
Mengyuan Li, Xingjiu Yang, Guoxin Zhang, Le Wang, Ziwei Zhu, Wenlong Zhang, Hao Huang, Ran Gao   +7 more
doaj   +1 more source

Experimental measurement-based quantum computing beyond the cluster-state model

, 2012
The paradigm of measurement-based quantum computation opens new experimental avenues to realize a quantum computer and deepens our understanding of quantum physics.
A Politi, A Politi, B Vaucher, C-Y Lu, Chao-Yang Lu, D Deutsch, D Gross, D Gross, D Gross, D Gross, D Perez-Garcia, F Verstraete, G Vallone, GK Brennen, He Lu, HF Hofmann, HJ Briegel, HJ Briegel, J Eisert, J-M Cai, JCF Matthews, Jian-Ming Cai, Jian-Wei Pan, JL O'Brien, K Kieling, M Bremner, M Fannes, M Mohseni, M Van den Nest, M Varnava, MA Nielsen, MS Tame, N Gisin, N Kiesel, N Kiesel, NK Langford, P Kalasuwan, P Walther, PG Kwiat, Ping Xu, R Okamoto, R Prevedel, R Raussendorf, SD Bartlett, Tao Yang, TC Ralph, WB Gao, Wei-Bo Gao, X Chen, Xing-Can Yao, Y Tokunaga, Yu-Ao Chen, Z-H Wei., Zeng-Bing Chen   +53 more
core   +1 more source

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

MedComm – Future Medicine
Mitochondria are the primary energy hubs of cells and are critical for maintaining cellular functions. However, aging leads to a decline in mitochondrial efficiency.
Lanlan Jia, Ziyu Wei, Jinyuan Luoqian, Xi Wang, Chao Huang   +4 more
doaj   +1 more source

Combined transcriptome and metabolome analysis reveals the regulatory network of histidine kinase QseC in the two-component system of Glaesserella parasuis

Frontiers in Microbiology
IntroductionGlaesserella parasuis (G. parasuis) causes agent Glässer’s disease in swine. This study investigated the mechanism of QseC in G. parasuis.MethodsThe study utilized transcriptomic and metabolomic sequencing techniques.
Xuefeng Yan, Yuhong Zhou, Songwei Liu, Congwei Gu, Congwei Gu, Wudian Xiao, Wudian Xiao, Mingde Zhao, Mingde Zhao, Zehui Yu, Zehui Yu, Lvqin He, Lvqin He   +12 more
doaj   +1 more source

Experimental Support for a Categorical Compositional Distributional Model of Meaning [PDF]

, 2011
Modelling compositional meaning for sentences using empirical distributional methods has been a challenge for computational linguists. We implement the abstract categorical model of Coecke et al.
Grefenstette, Edward, Sadrzadeh, Mehrnoosh   +1 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Chronic methanol exposure induces cognitive impairment and Alzheimer's‐like pathology in rhesus monkeys

Animal Models and Experimental Medicine
Background The absence of effective animal models for sporadic Alzheimer's disease (AD) remains a pivotal barrier to therapy development. Because methanol metabolism produces endogenous formaldehyde, a neurotoxic agent linked to cognitive decline, this ...
Hongwei Li, Changhua Shi, Keya Li, Xinjing Fu, Ying Lyu, Yanfeng Xu, Yunlin Han, Wei Liang, Qin Chuan, Ling Zhang   +9 more
doaj   +1 more source

Validation of a model of regulation in the tryptophan operon against multiple experiment data using global optimisation [PDF]

, 2009
This paper is concerned with validating a mathematical model of regulation in the tryptophan operon using global optimization. Although a number of models for this biochemical network are proposed, in many cases only qualitative agreement between the ...
Bates, D.G., Heslop-Harrison, P., Kim, J.-R., Kim, J.-S., Postlethwaite, I.   +4 more
core