Results 71 to 80 of about 8,545,961 (198)

Impact of variations in airborne microbiota on pneumonia infection: An exploratory study

Ecotoxicology and Environmental Safety
Background: Previous studies showed airborne bacteria affect pneumonia incidence, but specific impacts of bacterial communities on Klebsiella pneumoniae infection were unknown.
Li Zhou, Chenchen Song, Lianlian Zhao, Zhi Guo, Yuhan Lei, Yunlin Han, Kai Gao, Yanfeng Xu, Zhiguang Xiang, Baicun Li, Jianguo Guo   +10 more
doaj   +1 more source

Experimental Models for Psoriasis

Journal of Investigative Dermatology, 1990
Evidence suggests that inherent in skin of psoriatic subjects are cells, architectural structures, and/or mediators, which are, at a minimum, responsible for its hyperproliferative epidermis. An objective of our laboratory has been to establish an in vitro definition of this inherent aberration.
Krueger, G.G., Jorgensen, C.M.
openaire   +2 more sources

Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis

Frontiers in Pharmacology
IntroductionThis study aims to investigate the progressive impact of chronic iron overload on the olfactory bulb, a region significantly affected in early neurodegenerative diseases like Parkinson’s and Alzheimer’s. The focus is on understanding how iron
Lin Deng, Lin Deng, Lin Deng, Qihui Luo, Qihui Luo, Yucong Liu, Yucong Liu, Yao Wang, Yao Wang, Zongliang Xiong, Zongliang Xiong, Hongping Wang, Lu Zhao, Lanlan Jia, Lanlan Jia, Riyi Shi, Chao Huang, Chao Huang, Zhengli Chen, Zhengli Chen   +19 more
doaj   +1 more source

Experimental models [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2005
openaire   +4 more sources

Effect of PM2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens

Scientific Reports
Fine particulate matter 2.5 (PM2.5) is a prevalent atmospheric pollutant that is closely associated with asthma. Elderly patients have a high incidence of asthma with a long course of illness.
Lianlian Zhao, Xiaolin Ding, Li Zhou, Chenchen Song, Taisheng Kang, Yanfeng Xu, Yunpeng Liu, Yunlin Han, Wenjie Zhao, Boxiang Zhang, Dan Xu, Jianguo Guo   +11 more
doaj   +1 more source

The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function

Scientific Reports, 2017
Suppression of therapeutic transgene expression from retroviral gene therapy vectors by epigenetic defence mechanisms represents a problem that is particularly encountered in pluripotent stem cells (PSCs) and their differentiated progeny.
Jessica Kunkiel, Natascha Gödecke, Mania Ackermann, Dirk Hoffmann, Axel Schambach, Nico Lachmann, Dagmar Wirth, Thomas Moritz   +7 more
doaj   +1 more source

Androgen-responsive FOXP4 is a target for endometrial carcinoma

Communications Biology
Although low estrogen is considered to suppress uterine endometrial carcinoma, the most cases occur in the postmenopausal stage. After menopause, the production of androgen level also declines.
Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, Masanori Ono, Yasunari Mizumoto, Chiaki Takahashi, Hiroshi Fujiwara, Takiko Daikoku   +14 more
doaj   +1 more source

Dynamic stability analysis of a fractional calculus-based colon cancer model with therapeutic interventions

Scientific Reports
Colon cancer is a high-risk malignant tumor worldwide. To address the limited efficacy and overlapping toxicity of current chemoimmunotherapy, this study establishes a fractional-order colon cancer model with a core architecture capturing the probiotics-
Ruilei Tai, Zhaoyang Chen, Yanling Zhao, Ruiqing Shi   +3 more
doaj   +1 more source

Establishing essential oil stewardship through the case of rosemary and thyme oils against Staphylococcus aureus

Frontiers in Microbiology
Essential oils (EOs) have long been studied for their antimicrobial properties, yet most investigations rely on simplistic models, limited strain panels, and anecdotal interpretations—failing to meet the standards expected of modern anti-infective agents.
Malwina Brożyna, Zuzanna Stępnicka, Zuzanna Stępnicka, Katarzyna Kapczyńska, Bartłomiej Dudek, Adam Matkowski, Adam Junka   +6 more
doaj   +1 more source

Bone marrow mesenchymal stem cells derived cytokines associated with AKT/IAPs signaling ameliorate Alzheimer’s disease development

Stem Cell Research & Therapy
Background Alzheimer’s disease (AD) is a progressive neurodegenerative condition affecting around 50 million people worldwide. Bone marrow-derived mesenchymal stem cells (BMMSCs) have emerged as a promising source for cellular therapy due to their ...
Yalan Lu, Yanfeng Xu, Li Zhou, Siyuan Wang, Yunlin Han, Kewei Wang, Chuan Qin   +6 more
doaj   +1 more source