Results 91 to 100 of about 325,075 (311)

Applying modular design principles of adverse outcome pathways to experimental planning in toxicology

open access: yesEvidence-Based Toxicology
Adverse outcome pathways (AOPs) offer a modular framework that can transform experimental planning in toxicology beyond their current use in organising knowledge.
Devon A. Barnes   +2 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Evidence on the Value of Strategic Planning in Marketing: How Much Planning Should a Marketing Planner Plan? [PDF]

open access: yes
What evidence exists on the value of formal planning for strategic decision-making in marketing? This paper reviews the evidence. This includes two tests of face validity.
JS Armstrong, David J. Reibstein
core  

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Local development planning and bats in the UK : “an impenetrable fog” ?

open access: yes, 2011
This study was supported by RPS Group plc (Planning & Development)Despite national and international protection, and the focus of conservation biology research, UK bat populations remain under threat from development.
Cohen, Keith
core  

Planning through Automatic Portfolio Configuration: The PbP Approach

open access: yes, 2014
In the field of domain-independent planning, several powerful planners implementing different techniques have been developed. However, no one of these systems outperforms all others in every known benchmark domain.
Gerevini, Alfonso E.   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Portfolio Methods for Optimal Planning: an Empirical Analysis [PDF]

open access: yes, 2015
Combining the complementary strengths of several algorithms through portfolio approaches has been demonstrated to be effective in solving a wide range of AI problems. Notably, portfolio techniques have been prominently applied to suboptimal (satisficing)
Gerevini, Alfonso E.   +11 more
core   +1 more source

Tamanho de amostra de caracteres de genótipos de soja Sample size of the characters in soybeans genotypes

open access: yesCiência Rural, 2009
O objetivo deste trabalho foi estimar o tamanho de amostra necessária para avaliar caracteres de genótipos de soja (Glycine max L.) e verificar a variabilidade do tamanho de amostra entre genótipos e entre experimentos.
Alberto Cargnelutti Filho   +3 more
doaj  

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