Results 91 to 100 of about 1,466,559 (298)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Experimental plan for carrot culture
Ciência RuralABSTRACT: The carrotculture stands out on the world stage due to its nutritional characteristics and economic importance, an aspect that demands the constant development of research aiming greater productivity. Thus, this study proposed an experimental plan, determining the estimates of plot size, sample size, and number of repetitions, with the ...
Darlei Michalski Lambrecht +10 more
openaire +3 more sources
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
PLOT SIZE IN THE EVALUATION OF PAPAYA SEEDLINGS 'BAIXINHO DE SANTA AMÁLIA' IN TUBES
Revista Brasileira de FruticulturaWere evaluated three characters in papaya seedlings 'Baixinho de Santa Amália' to estimate the optimum plot size and the number of replications in a completely randomized experiment, a randomized block and Latin square.
HUMBERTO FELIPE CELANTI +4 more
doaj +1 more source
Public Confidence in the Judiciary: Some Notes and Reflections [PDF]
, 1970 Persons with intellectual disability have been found to perform more poorly on tasks, demanding the use of executive functions like planning, than their peers. This study investigated difficulties with planning, and how problems with planning ability can
Miller, Arthur Selwyn
core +1 more source
Conformant Planning via Symbolic Model Checking
, 2011 We tackle the problem of planning in nondeterministic domains, by presenting a new approach to conformant planning. Conformant planning is the problem of finding a sequence of actions that is guaranteed to achieve the goal despite the nondeterminism of ...
Cimatti, A., Roveri, M.
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Evidence-Based ToxicologyAdverse outcome pathways (AOPs) offer a modular framework that can transform experimental planning in toxicology beyond their current use in organising knowledge.
Devon A. Barnes +2 more
doaj +1 more source
A Parametric Hierarchical Planner for Experimenting Abstraction Techniques [PDF]
, 2003 This paper presents a parametric system, devised and implemented to perform hierarchical planning by delegating the actual search to an external planner (the "parameter") at any level of abstraction, including the ground one.
ARMANO, GIULIANO +2 more
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source