Results 81 to 90 of about 1,466,559 (298)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Geo-questionnaire in urban planning – preliminary results of the experimental application in Poland [PDF]

open access: yes, 2016
Changes in the attitude of local authorities towards the public participation in the decision making processes have prompted development of new methods of such involvement.
Brudka, Cezary   +6 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Necessity of the inclusion of borders in value of cultivation and use trials in upland rice

open access: yesRevista Agrogeoambiental, 2019
Experimental accuracy in crop research is directly affected by the size of plots. For this reason, researchers use empirical knowledge to determine plot size. There are also other important aspects for determining ideal plot size. These include the type
Marcelo Eduardo Forni de Mattos   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Robust Line Planning in case of Multiple Pools and Disruptions

open access: yes, 2011
We consider the line planning problem in public transportation, under a robustness perspective. We present a mechanism for robust line planning in the case of multiple line pools, when the line operators have a different utility function per pool.
A. Bessas   +3 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

SPRD: a surface plasmon resonance database of common factors for better experimental planning. [PDF]

open access: yesBMC Mol Cell Biol, 2021
Tiwari PB   +6 more
europepmc   +1 more source

Studies of planning behavior of aircraft pilots in normal, abnormal and emergency situations [PDF]

open access: yes
A methodology for the study of planning is presented and the results of applying the methodology within two experimental investigations of planning behavior of aircraft pilots in normal, abnormal, and emergency situations are discussed.
Hillmann, K.   +2 more
core   +1 more source

A Critical Look at the Abstraction Based on Macro-Operators [PDF]

open access: yes, 2004
ion can be an effective technique for dealing with the complexity of planning tasks. This paper is aimed at assessing and identifying in which cases abstraction can actually speed-up the overall search.
ARMANO G, CHERCHI G, VARGIU E
core  

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