Results 101 to 110 of about 1,456,951 (295)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Ciência Rural, 2009 O objetivo deste trabalho foi estimar o tamanho de amostra necessária para avaliar caracteres de genótipos de soja (Glycine max L.) e verificar a variabilidade do tamanho de amostra entre genótipos e entre experimentos.
Alberto Cargnelutti Filho +3 more
doaj
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
On the Effective Configuration of Planning Domain Models [PDF]
, 2015 The development of domain-independent planners within the AI Planning community is leading to “off the shelf” technology that can be used in a wide range of applications.
Chrpa, Lukáš +3 more
core
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Experimental plan for carrot culture
Ciência RuralABSTRACT: The carrotculture stands out on the world stage due to its nutritional characteristics and economic importance, an aspect that demands the constant development of research aiming greater productivity. Thus, this study proposed an experimental plan, determining the estimates of plot size, sample size, and number of repetitions, with the ...
Darlei Michalski Lambrecht +10 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Entropy generation and jet engine optimization
, 2010 In 2009, it was shown that, with an original approach to hydrodynamic cavitation, a phenomenological model was realized in order to compute some of the physical parameters needed for the design of the most common technological applications (turbo ...
Lucia, Umberto
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source