Results 111 to 120 of about 576,095 (300)
The reengineering of a software system for glaucoma analysis [PDF]
, 2005 Glaucoma is a destructive eye disease that causes blindness in individuals displaying little or no symptoms. There is no cure as yet though there are treatments that can arrest its effects or slow its development. The earlier the disease is detected, the
Fraser, R.G., Armarego, J., Yogesan, K.
core +1 more source
Reliability approach for safe designing on a locking system [PDF]
, 2010 The aim of this work is to predict the failure probability of a locking system. This failure probability is assessed using complementary methods: the First-Order Reliability Method (FORM) and Second-Order Reliability Method (SORM) as approximated methods,
ARNOUX, Philippe +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Creating an advanced software engineering laboratory by combining empirical studies with process simulation [PDF]
, 2022 4 S. : Ill., Lit.Laboratory experiments have been proven as an essential means for determining the effects of software engineering technologies. We propose the use of process simulation for adding a virtual capability to a software engineering laboratory
Münch, J., Rus, I., Rombach, H.D.
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Case-Based Reasoning for Experimental Software Engineering [PDF]
, 2007 1 Introduction S.1 2 Software Engineering S.1 3 Experimental Software Engineering S.6 4 CBR Support for Experimental Software Engineering S.9 5 State-of-the-Art S.11 6 Our Approach S.12 - 6.1 Case Representation S.12 - 6.2 Acquisition of Cases S ...
Tautz, C. +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
DISTANCE: a framework for software measure construction. [PDF]
In this paper we present a framework for software measurement that is specifically suited to satisfy the measurement needs of empirical software engineering research.
Dedene, Guido, Poels, Geert
core
MOPED: A Mobile Open Platform for Experimental Design of Cyber-Physical Systems [PDF]
, 2014 Due to the increasing importance of cyber-physical and embedded systems in industry, there is a strong demand for engineers with an updated knowledge on contemporary technology and methods in the area.
Johansson, Eilert, +14 more
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source