Results 91 to 100 of about 1,784,727 (289)

Automated requirements engineering framework for agile model-driven development

open access: yesFrontiers in Computer Science
IntroductionAdvances in requirements engineering, driven by various paradigms and methodologies, have significantly influenced software development practices.
Muhammad Aminu Umar   +3 more
doaj   +1 more source

UniMAP e-Lab for Electrical Engineering Technology: Future Online Laboratory Classes

open access: yesMATEC Web of Conferences, 2016
This paper will describe a proposed design and approaches to the future provision of laboratory experience using communication and control technology.
Daud Mohd Hisam, Razali Zol Bahri
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Are We Prepared for Simulation Based Studies in Software Engineering Yet?

open access: yesCLEI Electronic Journal, 2013
CONTEXT: Simulation-based studies have been used in different research areas in order to conduct computerized experiments with distinct purposes. However, it seems that Software Engineering simulation studies have been performed in a non-systematic way ...
Breno Bernard Nicolau de França   +1 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Nonlinear finite element analysis of reinforced concrete beams strengthened with textile fine grained mortar [PDF]

open access: yes, 2020
Nowadays, there was an increasing need of repairing and upgrading the reinforced concrete (RC) structure due to the deterioration of the structure. The fibre reinforced polymer (FRP) was commonly used for structural retrofitting purposes.
Abdul Hamid, Noor Azlina   +4 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Accurate Local Estimation of Geo-Coordinates for Social Media Posts [PDF]

open access: yes, 2014
Associating geo-coordinates with the content of social media posts can enhance many existing applications and services and enable a host of new ones. Unfortunately, a majority of social media posts are not tagged with geo-coordinates.
Dagnino, Aldo   +2 more
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Configuration management and product lines to enhance the replication process in software engineering [PDF]

open access: yes, 2012
This research is concerned with the experimental software engineering area, specifically experiment replication. Replication has traditionally been viewed as a complex task in software engineering.
Espinosa Gallardo, Edison Gonzalo
core  

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