The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Sentiment Analysis for Software Engineering Domain in Turkish
Sakarya University Journal of Computer and Information Sciences, 2020 The focus of this study is to provide a model to be used for the identification of sentiments of comments about education and profession life of software engineering in social media and microblogging sites.
Mansur Alp Toçoğlu
doaj +1 more source
Do the Fix Ingredients Already Exist? An Empirical Inquiry into the Redundancy Assumptions of Program Repair Approaches [PDF]
, 2014 Much initial research on automatic program repair has focused on experimental results to probe their potential to find patches and reduce development effort. Relatively less effort has been put into understanding the hows and whys of such approaches. For
Martinez, Matias +2 more
core +7 more sources
Improving Software Engineering Research Through Experimentation Workbenches [PDF]
, 2019 Experimentation with software prototypes plays a fundamental role in software engineering research. In contrast to many other scientific disciplines, however, explicit support for this key activity in software engineering is relatively small. While some approaches to improve this situation have been proposed by the software engineering community ...
Klaus Schmid +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Educational Application of Flow3D Software for Turbulent Modeling in 3D Simulation of Hydraulic Jump in Stilling Basin with Concrete Baffles [PDF]
Fanāvarī-i āmūzish, 2008 In this paper, hydraulic jump which is one of the effective means of energy dissipation of supercritical flow in hydraulic engineering is simulated using Flow 3D software.
S.R. Sabbagh Yazdi +2 more
doaj +1 more source
Deep tillage tool optimization by means of finite element method: Case study for a subsoiler tine [PDF]
, 2010 Technologies and computer capacity currently available allow us to employ design software and numerical methods to solve complicated problems in very wide disciplines of engineering. It is also important for researches in agriculture.
Akinci, Ibrahim +5 more
core
The Search for the Laws of Automatic Random Testing
, 2012 Can one estimate the number of remaining faults in a software system? A credible estimation technique would be immensely useful to project managers as well as customers.
Furia, Carlo A. +4 more
core +1 more source
Exploiting Semantics for Filtering and Searching Knowledge in a Software Development Context [PDF]
, 2014 Software development is still considered a bottleneck for SMEs (Small and Medium Enterprises) in the advance of the Information Society. Usually, SMEs store and collect a large number of software textual documentation; these documents might be profitably
BERGAMASCHI, Sonia +2 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source