Results 61 to 70 of about 576,095 (300)
Trends in robotic software frameworks [PDF]
S.259-266In the software community, a framework indicates an integrated set of domainspecific software components [CS95] which can be reused to create applications.
Vaughan, R. +8 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Knowledge discovery from software engineering measurement data [PDF]
S.450-458 : Ill., Lit.Knowledge discovery from software engineering measurement data is essential in deriving the right conclusions from performed experiments.
Morasca, S., Ruhe, G.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Delayed failure of software components using stochastic testing [PDF]
The present research investigates the delayed failure of software components and addresses the problem that the conventional approach to software testing is unlikely to reveal this type of failure. Delayed failure is defined as a failure that occurs some
Gardiner, Jeremy
core
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Municipal AI integration: a structured approach
This research aims to develop a structured approach for implementing Artificial Intelligence (AI) in municipal governance. The study addresses three key questions: (1) What principles can be derived from existing AI implementation frameworks?
Lutz Eichholz
doaj +1 more source
Lexicon-Enhanced LSTM With Attention for General Sentiment Analysis
Long short-term memory networks (LSTMs) have gained good performance in sentiment analysis tasks. The general method is to use LSTMs to combine word embeddings for text representation.
Xianghua Fu +4 more
doaj +1 more source

